Recent advances in understanding the diversity and functional roles of endogenous viral elements within the genomes of virus-transmitting vectors
During the long-term interaction between viruses and their hosts,certain viral sequences can be integrated into the host genomes,forming endogenous viral elements (EVEs). In addition to retrovi-ruses,recent advances in genomics and viromics have unveiled the presence of non-retroviral endog-enous RNA viral elements (nrEVEs) within eukaryotic genomes. Nevertheless,the functions of these identified EVEs or nrEVEs are poorly understood. Given the significant implications of vector-transmitted animal and plant viruses to public health for humans,animals,and plants,this review con-centrates on recent progress in research regarding EVEs,particularly nrEVEs,in the genomes of virus-transmitting vectors. This review summarizes the definition and discovery of EVE,diversity and func-tions of EVEs in important vectors,including mosquitoes,aphids,thrips,planthoppers,and ticks. Fur-thermore,this review also provides overview on future research in this field,which will contribute to re-vealing the long-term co-evolutionary relationship between RNA viruses and their hosts,and to develop-ing new pest control strategies.
万方数据
维普
