首页|自体带骨膜髂骨移植与同种异体骨骨粉联合PRP治疗距骨骨软骨损伤的治疗效果比较研究

自体带骨膜髂骨移植与同种异体骨骨粉联合PRP治疗距骨骨软骨损伤的治疗效果比较研究

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目的 分析并对比自体带骨膜髂骨移植与同种异体骨骨粉联合富血小板凝胶(platelet rich gel,PRP)治疗HeppleⅤ型距骨骨软骨损伤(osteochondral injury,OLT).方法 选取浙江中医药大学附属金华中医院 2018 年 10 月至 2022 年10 月收入的HeppleⅤ型OLT患者 62 例为研究对象,根据其治疗方式将其分为移植组(接受自体带骨膜髂骨移植治疗,31 例)、联合组(接受同种异体骨骨粉联合PRP治疗,31 例).对患者进行术后 12 个月门诊随访研究,评估并比较两组患者术后 12 个月治疗效果、踝关节活动度(range of motion,ROM)、美国骨科足踝外科学会(American Society of Orthopedic Foot and Ankle Surgeons,AOFAS)踝-后足评分、疼痛评分、满意度、并发症发生率差异.结果 移植组治疗总有效率(96.77%)与联合组(93.55%)相比,差异无统计学意义(P>0.05).术后 12 个月两组ROM、AOFAS评分均改善(P<0.05),组间差异无统计学意义(P>0.05).两组患者术后 1 个月、3 个月、6 个月、12 个月,两组疼痛评分均较术前有所降低(P<0.05).移植组患者主观总满意度(77.42%),低于联合组(96.77%,P<0.05).移植组并发症总发生率(19.35%)与联合组(3.23%)相比,明显更高(P<0.05).结论 同种异体骨骨粉联合PRP可避免额外手术切口,患者主观满意度更高,术后并发症发生率低.
Curative effect of autologous periosteal iliac bone graft and allogeneic bone powder combined with PRP on HeppleⅤ talus osteochondral injury
Objective To analyze and compare the treatment of HeppleⅤ talus osteochondral injury(OLT)with autologous periosteal iliac bone graft and allogeneic bone powder combined with platelet rich gel(PRP).Methods Totally 62 HeppleⅤOLT patients admitted to our hospital from October 2018 to October 2022 were selected as the research subjects.They were divided into a transplantation group(31 patients received autologous periosteal iliac bone transplantation treatment)and a combination group(31 patients received allogeneic bone powder combined with PRP treatment)based on their treatment methods.Conduct a 12 month postoperative outpatient follow-up study on patients,evaluate and compare the treatment effectiveness,ankle joint range of motion(ROM),American Society of Orthopedic Foot and Ankle Surgeons(AOFAS)ankle posterior foot score,pain score,satisfaction,and incidence of complications between the two groups of patients at 12 months after surgery.Results The total effective rate of the transplantation group(96.77%)was not significantly different from that of the combination group(93.55%,P>0.05).At 12 months after surgery,the ROM and AOFAS scores of both groups improved(P<0.05),and there was no statistically significant difference between the groups(P>0.05).At 1 month,3 months,6 months,and 12 months after surgery,the pain scores of both groups decreased compared to before surgery(P<0.05).The subjective overall satisfaction of patients in the transplantation group(77.42%)was lower than that in the combination group(96.77%,P<0.05).The total incidence of complications in the transplantation group(19.35%)was significantly higher than that in the combination group(3.23%,P<0.05).Conclusion Allogeneic bone powder combined with PRP can avoid additional surgical incisions,increase patient subjective satisfaction,and increase the incidence of postoperative complications.

Iliac bone with periosteumAllogeneic bone powderPlatelet rich gel(PRP)Osteochondral injury of talus(OLT)

吴苏琪、吴寒松、余冬梅、陈琼、池蓉蓉

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浙江中医药大学附属金华中医院骨伤二科,浙江金华 321000

带骨膜髂骨 异体骨骨粉 富血小板凝胶 距骨骨软骨损伤

浙江省金华市科学技术局科学研究基金项目

2019-4-057

2024

中国现代医生
中国医学科学院

中国现代医生

影响因子:1.571
ISSN:1673-9701
年,卷(期):2024.62(5)
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