Meta-analysis of the association between late-life depression and mild cognitive impairment
Objective To systematically evaluate the correlation between elderly depression and mild cognitive impairment.Methods We searched the CNKI,VIP,WanFang Data,Cochrane Library,EMbase,Pubmed,and Web of Science databases using computer,and collected cohort studies on the correlation between elderly depression and mild cognitive impairment.The search time limit was from the establishment of the database to July 6,2023.Two researchers independently completed the literature screening,data extraction,and quality evaluation,and conducted a Meta-analysis using Review Manager 5.4 software.Results A total of 10 articles were included,with a total sample size of 26 813 people.The Meta-analysis showed that there was a correlation between elderly depression and mild cognitive impairment(OR=1.47,95%CI:1.25-1.72,P<0.001).Conclusion Current evidence indicates that elderly depression is one of the risk factors for the development of mild cognitive impairment.This conclusion is limited by the type,quality,and quantity of research,and needs to be validated by more high-quality research.
万方数据
维普
