首页|从震颤分析评估特发性震颤与ET-PD进展

从震颤分析评估特发性震颤与ET-PD进展

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目的 探讨原发性帕金森病(idiopathic Parkinson's disease,IPD)患者、特发性震颤(essential tremor,ET)患者与特发性震颤发展为帕金森病(Parkinson's disease developed from esential tremor,ET-PD)患者的震颤特征的差异.方法 分别纳入IPD患者 30 例、ET30 例及ET-PD患者 20 例,比较 3 组静止性、姿势性震颤的频率、收缩型式及有无谐波的差异.结果 IPD组、ET组和ET-PD组 3 组患者在发病年龄、病程、统一帕金森病评定量表(essential tremor,UPDRS)评分上差异均有统计学意义(P<0.01).IPD组、ET组和ET-PD组 3组患者静止性震颤平均震颤频率、姿势性震颤的平均震颤频率、静止状态下出现交替性震颤比率、姿势状态下出现交替性震颤比率、静止状态下谐波出现率差异有统计学意义(P<0.05),姿势状态下谐波出现率差异均有统计学意义(P<0.05).结论 IPD组、ET组与ET-PD组分别具有明显差异的震颤特点.ET-PD组兼具二者的特点,又有其独特性,震颤分析有助于该病的识别.
Evaluating the outcome of idiopathic tremor through tremor analysis
Objective To explore the differences in tremor characteristics between patients with primary Parkinson's disease(IPD),essential tremor(ET),and Parkinson's disease developed from essential tremor(ET-PD).Method Thirty IPD patients,30 ETs,and 20 ET-PD patients were included,and the frequency,contraction pattern,and presence of harmonics of static and postural tremors were compared among the three groups.Results There were statistically significant differences(P<0.01)among the IPD group,ET group,and ET-PD group in terms of age of onset,disease course,and the unified Parkinson's disease rating scale(UPDRS)score.There were statistically significant differences(P<0.05)in the average frequency of stationary tremors,average frequency of postural tremors,rate of alternating tremors in stationary state,rate of alternating tremors in postural state,and rate of harmonic occurrence in stationary state among the IPD group,ET group,and ET-PD group,as well as in the rate of harmonic occurrence in postural state(P<0.05).Conclusion The IPD group,ET group,and ET-PD group each have significant differences in tremor characteristics.The ET-PD group has both characteristics and uniqueness,and tremor analysis can help identify this disease.

Idiopathic tremor developing into Parkinson's diseaseParkinson's diseaseTremorElectromyography

亓爱芹、刘烨辉、贺凤娇

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山东第一医科大学附属人民医院神经内科,山东济南 271199

特发性震颤发展为帕金森病 帕金森病 震颤 肌电描记术

山东省济南市科技局临床医学科技创新计划济南市卫生健康委科技计划(第二批)(2020)

2020190752020-4-135

2024

中国现代医生
中国医学科学院

中国现代医生

影响因子:1.571
ISSN:1673-9701
年,卷(期):2024.62(8)
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