中国现代医生2024,Vol.62Issue(9) :30-32.DOI:10.3969/j.issn.1673-9701.2024.09.007

妊娠期A型肉毒毒素暴露对妊娠结局的影响

Effect of botulinum toxin A exposure during pregnancy on pregnancy outcome

蔡宇庭 周晓媚
中国现代医生2024,Vol.62Issue(9) :30-32.DOI:10.3969/j.issn.1673-9701.2024.09.007

妊娠期A型肉毒毒素暴露对妊娠结局的影响

Effect of botulinum toxin A exposure during pregnancy on pregnancy outcome

蔡宇庭 1周晓媚1
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作者信息

  • 1. 杭州市妇产科医院药剂科,浙江杭州 310008
  • 折叠

摘要

目的 回顾性分析妊娠期A型肉毒毒素(botulinum toxin A,BTX-A)暴露孕妇的妊娠结局,为临床医生指导妊娠期女性安全用药提供参考.方法 调查 2017 年 1 月至 2023 年 3 月在杭州市妇产科医院用药咨询门诊就诊的妊娠期或妊娠前 3 个月内BTX-A暴露孕妇的妊娠结局.结果 共收集 17 例妊娠期或妊娠前 3 个月内BTX-A暴露孕妇案例.8 例已知妊娠结局,其中 1 例胎儿存在出生缺陷,出生缺陷发生率为 12.5%;其余 9 例均要求早期人工流产.结论 妊娠期暴露于BTX-A很可能是安全的,但仍需进一步的研究证实.

Abstract

Objective To retrospectively analyze the pregnancy outcome of pregnant women exposed to botulinum toxin A(BTX-A)during pregnancy,so as to provide experience for clinicians to guide safe drug use in pregnant women.Methods To investigate the pregnancy outcome of pregnant women exposed to BTX-A during pregnancy or the last three months before pregnancy who visited the medication consultation clinic of Hangzhou Women's Hospital from January 2017 to March 2023.Results A total of 17 pregnant women exposed to BTX-A during pregnancy or the last three months before pregnancy were included in this study.Specifically,8 cases had known pregnancy outcomes,among which 1 case had birth defect with the ratio accounting for 12.5%,while the remaining 9 cases required early induced abortion.Conclusion Exposure to BTX-A during pregnancy is probably safe,but further studies are needed.

关键词

妊娠期/A型肉毒毒素/妊娠结局

Key words

Pregnancy/Botulinum toxin A/Pregnancy outcome

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基金项目

浙江省医药卫生科技计划(2019KY529)

出版年

2024
中国现代医生
中国医学科学院

中国现代医生

影响因子:1.571
ISSN:1673-9701
参考文献量14
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