首页|畲药活血降压贴联合体外反搏治疗H型1级高血压的临床效果观察

畲药活血降压贴联合体外反搏治疗H型1级高血压的临床效果观察

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目的 观察畲药活血降压贴联合体外反搏对H型1级高血压血瘀证患者的临床疗效.方法 选取2022年1月至2023年12月于丽水市中医院就诊的H型1级高血压血瘀证患者64例,采用随机数字表法分为对照组(西药+体外反搏)和观察组(西药+体外反搏+畲药活血降压贴),每组32例,疗程均为8周.比较两组患者的临床疗效、治疗前后中医证候积分、诊室收缩压(clinical systolic blood pressure,CSBP)、诊室舒张压(clinical diastolic blood pressure,CDBP)、脉搏波传导速度(brachial-ankle pulse wave velocity,baPWV)及踝臂指数(ankle brachial index,ABI)、肾素、醛固酮(aldosterone,ALD)、血管紧张素 Ⅱ(angiotensin Ⅱ,Ang Ⅱ)、同型半胱氨酸(homocysteine,Hcy)的差异,并记录不良反应.结果 治疗8周后,观察组患者的降压总有效率(93.75%)优于对照组(75.00%)(P<0.05);且观察组患者的中医证候积分低于对照组,差异有统计学意义(P<0.05);两组患者的CSBP、CDBP、baPWV均较治疗前下降,且观察组低于对照组(P<0.05);两组患者的ABI均较治疗前明显升高,且观察组高于对照组(P<0.05);两组患者的肾素、ALD、Ang Ⅱ和Hcy水平均较治疗前下降,且观察组低于对照组(P<0.05);两组患者均未出现严重不良反应.结论 畲药活血降压贴联合体外反搏治疗H型1级高血压血瘀证患者,可较好缓解临床症状,降低血压、肾素、醛固酮、血管紧张素Ⅱ和同型半胱氨酸水平,减轻动脉硬化僵硬度,值得临床推广应用.
Observation of the clinical efficacy of She medicine Huoxue Jiangya Tie combined with external counterpulsation in the treatment of type H grade 1 hypertension
Objective To observe the clinical efficacy of She medicine Huoxue Jiangya Tie combined with external counterpulsation on patients with type H grade 1 hypertension with blood stasis syndrome.Methods A total of 64 patients with type H grade 1 hypertension with blood stasis syndrome were selected from Lishui Hospital of Traditional Chinese Medicine from January 2022 to December 2023.According to the principle of random control,they were divided into control group(western medicine+external counterpulsation)and observation group(She medicine Huoxue Jiangya Tie+western medicine+external counterpulsationon),with 32 cases in each group,the duration of treatment was 8 weeks.The difference on clinical efficacy between two groups,traditional Chinese medicine syndrome scores,clinical systolic blood pressure(CSBP),clinical diastolic blood pressure(CDBP),brachial-ankle pulse wave velocity(baPWV),ankle brachial index(ABI),renin,aldosterone(ALD),angiotensin Ⅱ(Ang Ⅱ),homocysteine(Hcy)before and after treatment,between two groups were compared,and recorded adverse reactions.Results After 8 weeks of treatment,the total effective rate of blood pressure reduction in observation group(93.75%)was better than that in control group(75.00%)(P<0.05);And the traditional Chinese medicine syndrome score of observation group was lower than that of control group,with a statistically significant difference(P<0.05);The CSBP,CDBP,and baPWV of both groups of patients decreased compared to before treatment,and observation group was lower than control group(P<0.05);The ABI of both groups significantly increased compared to treatment,and observation group was higher than control group(P<0.05);The levels of renin,ALD,Ang Ⅱ,and Hcy in both groups decreased compared to before treatment,and observation group was lower than control group(P<0.05);Both groups of patients did not experience serious adverse reactions.Conclusion She medicine Huoxue Jiangya Tie combined with external counterpulsation in the treatment of type H grade 1 hypertension patients with blood stasis syndrome can better alleviate clinical symptoms,reduce blood pressure,renin,ALD,AngⅡ and Hcy levels,and reduce arteriosclerosis stiffness,which is worthy of clinical application.

She medicine Huoxue Jiangya TieExternal counterpulsationType H hypertensionBlood stasis syndrome

侯高飞、潘铨、陈礼平

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浙江中医药大学第三临床医学院,浙江杭州 310051

丽水市中医院心血管内科,浙江丽水 323000

畲药活血降压贴 体外反搏 H型高血压 血瘀证

浙江省中医药科技计划项目浙江中医药大学校级科研项目浙江省中青年临床名中医培养项目丽水市医学重点学科建设项目

2021ZB3412023FSYYZY49浙中医药[2021]22号3601017

2024

中国现代医生
中国医学科学院

中国现代医生

影响因子:1.571
ISSN:1673-9701
年,卷(期):2024.62(21)
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