首页|畲药活血降压舒心方治疗高血压伴焦虑患者的疗效观察

畲药活血降压舒心方治疗高血压伴焦虑患者的疗效观察

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目的 观察畲药活血降压舒心方对高血压伴焦虑患者白细胞介素(interleukin,IL)-6、IL-10 和焦虑自评量表(self-rating anxiety scale,SAS)评分的影响.方法 选取 2022 年 9 月至 2024 年 1 月于丽水市中医院就诊的 72 例高血压伴焦虑患者为研究对象,根据随机数字表法将其分为对照组和试验组,每组各 36 例.对照组给予氨氯地平治疗,试验组给予畲药活血降压舒心方+氨氯地平治疗,疗程均为 8 周.比较两组患者的疗效、中医证候积分、血压、IL-6、IL-10及SAS评分.结果 试验组患者的总有效率显著高于对照组(χ2=36.891,P<0.001).治疗后,试验组患者的中医证候积分、收缩压、舒张压、IL-6 水平及SAS评分均显著低于对照组,IL-10 水平显著高于对照组(P<0.05).结论 畲药活血降压舒心方联合氨氯地平治疗高血压伴焦虑患者疗效良好,可改善患者体内炎症水平,增强机体免疫调节能力,值得临床广泛应用.
Observation on the curative effect of She medicine Huoxue Jiangya Shuxin prescription on patients with hypertension and anxiety
Objective To observe the effects of She medicine Huoxue Jiangya Shuxin prescription on interleukin(IL)-6,IL-10 and self-rating anxiety scale(SAS)scores in patients with hypertension and anxiety.Methods A total of 72 patients with hypertension and anxiety who were treated in Lishui Hospital of Traditional Chinese Medicine from September 2022 to January 2024 were selected as study objects,and were divided into control group and experimental group according to random number table method,with 36 cases in each group.The control group was treated with amlodipine,and the experimental group was treated with Huoxue Jiangya Shuxin prescription+amlodipine,the course of treatment was 8 weeks.The efficacy,TCM syndrome score,blood pressure,IL-6,IL-10 and SAS scores were compared between two groups.Results The total effective rate of experimental group was significantly higher than that of control group(χ2=36.891,P<0.001).After treatment,the TCM syndrome score,systolic blood pressure,diastolic blood pressure,IL-6 level and SAS score of experimental group were significantly lower than those of control group,and IL-10 level was significantly higher than that of control group(P<0.05).Conclusion She medicine Huoxue Jiangya Shuxin prescription combined with amlodipine in treatment of hypertension with anxiety patients with good effect,can improve the level of inflammation in patients,enhance immune regulation ability,worthy of clinical wide application.

She medicineHuoxue Jiangya Shuxin prescriptionInterleukin-6Interleukin-10Self-rating anxiety scale

戈子怡、潘铨、陈礼平

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浙江中医药大学第三临床医学院,浙江杭州 310053

丽水市中医院心血管内科,浙江丽水 323000

畲药 活血降压舒心方 白细胞介素-6 白细胞介素-10 焦虑自评量表

浙江省中医药科技计划项目浙江省中青年临床名中医培养项目丽水市医学重点学科建设

2021ZB341浙中医药[2021]22号3601017

2024

中国现代医生
中国医学科学院

中国现代医生

影响因子:1.571
ISSN:1673-9701
年,卷(期):2024.62(22)
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