目的 探究小儿感染性肺炎肺脏超声表现及与血清淀粉样蛋白A(serum amyloid protein A,SAA)/超敏C反应蛋白(hypersensitive C-reactive protein,hs-CRP)、降钙素原(procalcitonin,PCT)的联合诊断价值.方法 选取中国人民解放军联勤保障部队第九○三医院2019年1月至2023年6月收治的107例感染性肺炎患儿作为研究组,选取同期入院体检的50名健康儿童作为对照组.两组儿童均行肺脏超声检查,分析感染性肺炎患儿的超声表现;比较SAA/hs-CRP、PCT,并分析肺脏超声与SAA/hs-CRP、PCT联合检测对小儿感染性肺炎的诊断价值.结果 107例感染性肺炎患儿经肺脏超声诊断阳性104例,阳性率97.20％.研究组患儿肺脏超声评分、SAA/hs-CRP、PCT高于对照组(P＜0.05).重症感染性肺炎患儿肺脏超声评分、SAA/hs-CRP、PCT高于轻症患儿(P＜0.05).肺脏超声与SAA/hs-CRP、PCT联合检测对小儿感染性肺炎的诊断效能优于单独检测,曲线下面积为0.923,敏感度、特异性分别为92.30％、87.98％.肺脏超声评分与SAA/hs-CRP、PCT呈正相关(P＜0.05).结论 肺脏超声可显示感染性肺炎患儿的肺部病变特征,患儿超声表现多为胸膜线异常、B线增多、肺实变,与SAA/hs-CRP、PCT联合检测可进一步提高对小儿感染性肺炎的诊断效能.
The diagnostic efficacy of pulmonary ultrasound,SAA/hs-CRP,and PCT in pediatric infectious pneumonia
Objective To explore the pulmonary ultrasound manifestations of pediatric infectious pneumonia and its combined diagnostic value with serum amyloid protein A(SAA)/hypersensitive C-reactive protein(hs-CRP)and procalcitonin(PCT).Methods A tatol of 107 children with infectious pneumonia admitted to the 903rd Hospital of the Joint Logistics Support Force of the People's Liberation Army of China from January 2019 to June 2023 were selected as the research group,and 50 healthy children who underwent physical examinations during the same period were selected as the control group.Both groups of children underwent lung ultrasound examination to analyze the ultrasound manifestations of children with infectious pneumonia,compare SAA/hs-CRP and PCT,and analyze the diagnostic value of lung ultrasound combined with SAA/hs-CRP and PCT detection for pediatric infectious pneumonia.Results Among 107 children with infectious pneumonia,104 were diagnosed positive by lung ultrasound,with a positive rate of 97.20％.The lung ultrasound score,SAA/hs-CRP,and PCT of the study group were higher than those of the control group(P＜0.05).The lung ultrasound score,SAA/hs-CRP,and PCT in children with severe infectious pneumonia were higher than those in mild cases(P＜0.05).The diagnostic efficacy of lung ultrasound combined with SAA/hs-CRP and PCT detection for pediatric infectious pneumonia is superior to that of individual detection,with a curve area of 0.923,sensitivity and specificity of 92.30％and 87.98％,respectively.The lung ultrasound score is positively correlated with SAA/hs-CRP and PCT(P＜0.05).Conclusion Pulmonary ultrasound can display the characteristics of pulmonary lesions in children with infectious pneumonia.The ultrasound manifestations of children are mostly abnormal pleural lines,increased B-lines,and pulmonary consolidation.Combined detection with SAA/hs-CRP and PCT can further improve the diagnostic efficiency of pediatric infectious pneumonia.
Pediatric infectious pneumoniaPulmonary ultrasoundUltrasound manifestationsSerum amyloid protein AHypersensitivity C-reactive proteinProcalcitonin
万方数据
维普
