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基于数据挖掘探析肺癌患者术后调治的用药规律

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目的 基于数据挖掘探析肺癌患者术后调治的用药规律.方法 收集2009年9月至2023年12月于安徽中医药大学第一附属医院徐经世门诊诊治的肺癌患者的中药处方,应用古今医案云平台,对处方用药进行性、味、归经统计,分析药物的频次、关联规则、聚类及核心处方复杂网络.结果 共纳入中药处方171首,涉及中药156味,除烦、止呕、清热解毒的药物功效应用位例前3.归经以归肺经为主,性味以微寒、平、甘为主.高频(频次>30次)药物有北沙参、竹茹、甘草等20味.聚类分析组合5个,关联规则83条.核心处方为北沙参、竹茹、甘草、芦根、桔梗、橘络、酸枣仁、远志、麦冬、仙鹤草.结论 肺癌术后应从肺脾论治,遵循用药宜轻灵、随证加减的组方原则,扶正祛邪、安中化痰的治疗原则.
Drug use patterns in the treatment of lung cancer patients after surgery based on data mining
Objective To explore drug use patterns in treatment of lung cancer patients after surgery based on data mining.Methods The prescriptions of patients with lung cancer who were diagnosed and treated in the outpatient department of the First Affiliated Hospital of Anhui University of Chinese Medicine from September 2009 to December 2023 were collected.Based on the Cloud Platform of Ancient And Modern Medical Records,data mining method was used to analyze the nature and taste of drugs,meridian affinity,frequency,association rule,cluster and core prescription complex network.Results A total of 171 traditional Chinese medicine prescriptions were collected,involving 156 traditional Chinese medicines,and the top three drug effects were eliminating annoyance,stopping vomiting,clear heat and remove toxins.The main channel was the lung meridian,nature and taste were mainly slightly cold,flat and sweet.The high frequency(frequency>30 times)drugs included 20 flavors such as coastal glehnia root,bamboo shavings,and liquorice root.There were 5 cluster analysis combinations and 83 associationrules.The core prescriptions were coastal glehnia root,bamboo shavings,liquorice root,reed rhizome,platycodon root,inner fiber of orange peel,spine date seed,milkwort root,dwarf lilyturf tuber,hairyvein agrimonia herb.Conclusion After surgery,lung cancer should be treated from the lung and spleen,following the prescription principles of light spirit,increasing and decreasing with the syndrome,reinforce healthy qi to eliminate pathogenic factors,and eliminating phlegm.

Lung cancerTreatment after surgeryData miningDrug use patterns

高旭、张东伟

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安徽中医药大学研究生院,安徽 合肥 230012

安徽中医药大学第一附属医院肿瘤一科,安徽 合肥 230031

肺癌 术后调治 数据挖掘 用药规律

安徽省第二批省级中医优势(特色)专科建设优势专科

皖中医药服务秘[2022]34号

2024

中国现代医生
中国医学科学院

中国现代医生

影响因子:1.571
ISSN:1673-9701
年,卷(期):2024.62(28)