Analysis of the effect of imitation of bioelectricity stimulus combined with hormone in promoting endometrial repair and preventing intrauterine adhesion after missed abortion
Objective To explore the effect of imitation of bioelectricity stimulus combined with estrogen and progesterone on promoting endometrial repair and preventing intrauterine adhesion after missed abortion.Methods A total of 120 patients with missed abortion treated in Shenzhen Nanshan Maternal and Child Health Care Hospital from June 2021 to December 2022 were selected as the research objects.The patients were numbered according to the order of admission,and they were divided into control group (n=60) and combined group (n=60) according to the random number table method.Both groups were treated with curettage after medical abortion.The control group was treated with estrogen and progesterone,and combined group was treated with imitation of bioelectricity stimulus on the basis of control group.The duration of postoperative abdominal pain,visual analogue scale (VAS) score of abdominal pain 72 hours after operation,endometrial thickness,the end-systolic peak/end-diastolic peak (S/D),pulsation index (PI) and resistance index (RI) on the day after operation,15 days after operation and 15 days after the first menstrual onset were compared between two groups.The incidence of intrauterine adhesions in two groups was counted.Results The duration of postoperative abdominal pain and VAS score of abdominal pain at 72 hours after operation in combined group were significantly lower than those in control group (P<0.05).The endometrial thickness of combined group was higher than that of control group 15 days after operation and 15 days after the first menstrual onset,and S/D,PI and RI were lower than those of control group (P<0.05).During the treatment,the incidence of intrauterine adhesion in combined group was 3.33％,which was significantly lower than 13.33％ in control group (P<0.05).Conclusion Compared with the use of estrogen and progestins alone,imitation of bioelectricity stimulus combined with estrogen and progesterone can more effectively repair the endometrium and prevent the occurrence of intrauterine adhesion in patients with missed abortion,which is worthy of clinical promotion.
Imitation of bioelectricity stimulusMissed abortionIntrauterine adhesionEndometrial repair
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