Observation on the clinical effect of Tiaoshen Yangxin decoction in treating insomnia during perimenopause
Objective To observe the clinical effect of Tiaoshen Yangxin decoction on insomnia in perimenopausal patients with heart-kidney disharmony type.Methods From July 2022 to July 2023,60 patients with perimenopausal insomnia of heart-kidney disharmony type who met the diagnostic criteria were selected from Tongde Hospital of Zhejiang Province.The patients were divided into control group and experimental group by random number table method,30 cases in each group.The patients in control group were treated with Wuling capsule,and the patients in experimental group were treated with Tiaoshen Yangxin decoction.Before treatment and 8 weeks after treatment,the Pittsburgh sleep quality index (PSQI) score,Kupperman menopause index (KMI) score,Hamilton anxiety scale (HAMA) and TCM syndrome score were compared between two groups.Results After 8 weeks of treatment,the total effective rate of experimental group patients was 96.7％,which was higher than that of control group's 86.7％ (x2=17.153,P=0.000);The scores of the symptom of hot flashes,sweating,insomnia,palpitations,etc.in experimental group patients were lower than those in control group (P<0.05);The HAMA score and TCM syndrome score of experimental group patients after treatment were lower than those of control group (P<0.05).Conclusion The curative effect of Tiaoshen Yangxin decoction on insomnia in perimenopausal patients is better than that of Wuling capsule.In addition,Tiaoshen Yangxin decoction can also improve the symptoms of hot flashes,sweating,palpitations in perimenopausal insomnia patients and relieve anxiety.
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