首页|联合血液净化模式在中老年透析患者症状体征及睡眠质量中的应用研究

联合血液净化模式在中老年透析患者症状体征及睡眠质量中的应用研究

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目的 探讨联合血液净化模式对中老年透析患者症状体征及睡眠质量的影响.方法 采用方便抽样法选取长期在东部战区总医院血液净化中心接受规律透析的80例中老年患者作为研究对象,分为单一模式组和联合模式组,每组40例.单一模式组每周3次高通量血液透析治疗,联合模式组每周2次高通量血液透析及1次血液透析滤过.采用自行编制问卷,及症状指数量表比较两组患者的症状发生率、发生频率、严重度和困扰程度.采用匹兹堡睡眠量表评估两组患者的睡眠质量.结果 联合模式组患者的多项症状体征优于单一模式组,尤其是瘙痒、困难、口干、皮肤干燥4个核心症状(P<0.05);联合模式组患者睡眠质量明显优于单一模式组(P<0.01).两组患者在主观睡眠质量、睡眠潜伏期、睡眠障碍、日间功能障碍4个维度比较,差异有统计学意义(P<0.05).结论 应用联合血液净化模式中老年透析患者多维症状体征及睡眠质量治疗效果更优.
Combined blood purification model in the application of symptoms and signs and sleep quality in middle-aged and elderly dialysis patients
Objective To explore the application effect of combined blood purification mode in the symptoms and signs and sleep quality of middle-aged and elderly dialysis patients.Methods Convenient sampling method was used to select 80 patients who underwent regular dialysis at the Bblood Purification Center of the Jinling Hospital of Medical school of Nanjing University for a period of time.Patients were divided into only hemodialysis group and combined mode groups with 40 patients in each group.The only mode group received high-flux hemodialysis treatment 3 times a week,while combined mode group received high-flux hemodialysis twice a week and hemodiafltrationon once a week.Self-designed questionnaire and symptom index scale were used to compare incidence,frequency,severity and distress of symptoms between two groups.Patient sleep quality was assessed using Pittsburgh sleep quality index scale.Results Combined mode group was superior to only hemodialysis group in many symptoms and signs,especially pruritus,difficulty sleeping(P<0.01),dry mouth and dry skin(P<0.05).The sleep quality of combined mode group was significantly better than that of only hemodialysis group(P<0.01).There were significant differences in subjective sleep quality,sleep latency,sleep disorder and daytime dysfunction between two groups(P<0.05).Conclusion Combined blood purification mode has better effect on multi-dimensional symptoms,signs and sleep quality in middle-aged and elderly dialysis patients.

Middle-aged and elderly dialysis patientsSymptoms and signsCombined blood purification modeSleep quality

吕璇、鲁春红、孔凌、章明凤、张梦雅

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东部战区总医院(南京大学医学院附属金陵医院)国家肾脏疾病临床医学研究中心,江苏南京 210002

中老年透析患者 症状体征 联合血液净化模式 睡眠质量

2024

中国现代医生
中国医学科学院

中国现代医生

影响因子:1.571
ISSN:1673-9701
年,卷(期):2024.62(35)