Objective To explore the application effect of combined blood purification mode in the symptoms and signs and sleep quality of middle-aged and elderly dialysis patients.Methods Convenient sampling method was used to select 80 patients who underwent regular dialysis at the Bblood Purification Center of the Jinling Hospital of Medical school of Nanjing University for a period of time.Patients were divided into only hemodialysis group and combined mode groups with 40 patients in each group.The only mode group received high-flux hemodialysis treatment 3 times a week,while combined mode group received high-flux hemodialysis twice a week and hemodiafltrationon once a week.Self-designed questionnaire and symptom index scale were used to compare incidence,frequency,severity and distress of symptoms between two groups.Patient sleep quality was assessed using Pittsburgh sleep quality index scale.Results Combined mode group was superior to only hemodialysis group in many symptoms and signs,especially pruritus,difficulty sleeping(P<0.01),dry mouth and dry skin(P<0.05).The sleep quality of combined mode group was significantly better than that of only hemodialysis group(P<0.01).There were significant differences in subjective sleep quality,sleep latency,sleep disorder and daytime dysfunction between two groups(P<0.05).Conclusion Combined blood purification mode has better effect on multi-dimensional symptoms,signs and sleep quality in middle-aged and elderly dialysis patients.
关键词
中老年透析患者/症状体征/联合血液净化模式/睡眠质量
Key words
Middle-aged and elderly dialysis patients/Symptoms and signs/Combined blood purification mode/Sleep quality