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70例儿童人偏肺病毒肺炎的临床特征

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目的 探讨儿童人偏肺病毒(human metapenu-movirus,hMPV)肺炎的临床特征.方法 收集 2023 年 4 月至 2024年 3 月入住安徽医科大学第一附属医院儿科的 70 例hMPV肺炎患儿的临床资料,分析儿童hMPV肺炎的流行病学特点、临床表现、实验室及影像学特点、治疗和转归.结果 儿童hMPV肺炎多见于≤5 岁儿童(55 例),发病集中在春季(36例),54.3%患儿合并细菌感染.临床症状、体征:咳嗽(70 例),发热(65 例),气促(7 例)、喘息(19 例).48 例肺部可闻及啰音,其中湿啰音 38 例.34 例患儿C反应蛋白升高,7 例患儿降钙素原升高.X线胸片:斑片状阴影 55 例,肺实变 7 例,网格状、磨玻璃影 8 例.治疗:合并细菌感染应用抗菌药物 38 例,应用糖皮质激素治疗 29 例,肺泡灌洗9 例,氧疗 2 例,应用丙种球蛋白治疗 1 例,均未予抗病毒药物,无机械通气.患儿住院天数 3~15d,平均住院 5.7d.所有患儿均好转出院.结论 儿童hMPV肺炎≤5 岁儿童易感,集中在春季.hMPV肺炎患儿均有咳嗽,多伴发热,较易合并细菌感染,整体预后良好.
Clinical characteristics of 70 children with human metapenu-movirus pneumonia
Objective To explore the clinical characteristics of human metapenu-movirus(hMPV)pneumonia in children.Methods Epidemiological characteristics clinical manifestation,laboratory examination,imaging features,treatment and outcome of 70 hMPV pneumonia in children who were admitted to Department of Pediatrics,the First Affiliated Hospital of Anhui Medical University from April 2023 to March 2024 were collect and analyzed.Results hMPV pneumonia predominantly affected children under 5 years old(55 cases),with a higher incidence in spring(36 cases),and 54.3%with bacterial infection.Clinical manifestation included coughing(70 cases),fever(65 cases),breathlessness(7 cases),and wheezing(19 cases).48 cases had lung rales,38 cases were wet rales.34 cases showed elevated C-reactive protein and elevated procalcitonin in 7 cases.Chest X-ray showed 55 cases of patchy shadows,7 cases of lung consolidation,and 8 cases of gridded or ground glass shadows.38 cases were complicated with bacterial infections and treated with antibiotics,29 cases were treated with glucocorticoids,9 cases with bronchoalveolar lavage,2 cases with oxygen therapy,and 1 case with immunoglobulin,none required antiviral drugs or mechanical ventilation.Hospital stays varied between 3 and 15 days,averaged at 5.7 days.All cases improved and were discharged from the hospital.Conclusion hMPV pneumonia usually occurs in children less than or equal to 5 years old,and tends to occur in spring.Children with hMPV pneumonia were mainly characterized by fever and cough,bacterial co-infection is more common.The overall prognosis is good.

Human metapenu-movirusCommunity acquired pneumoniaHuman metapenu-movirus pneumoniaChildrenClinical features

李莉、翟爱国、王建

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安徽医科大学第一附属医院儿科,安徽合肥 230022

人偏肺病毒 社区获得性肺炎 人偏肺病毒肺炎 儿童 临床特征

2024

中国现代医生
中国医学科学院

中国现代医生

影响因子:1.571
ISSN:1673-9701
年,卷(期):2024.62(36)