Research status and development thinking of network toxicology in safety evaluation of traditional Chinese medicine
In view of the current stage of network toxicology research,the characteristics,practical application and development status of network toxicology in the safety research of traditional Chinese medicine were systematically reviewed.The research methods and supporting tools of network toxicology were summarized.The network toxicology was used to predict the adverse outcomes of traditional Chinese medicine,toxicity mechanism analysis,harmful component prediction,multidisciplinary cross-application,and omics technology.Focus on the shortcomings of current network toxicology and put forward preliminary solutions and improvement plans for colleagues to refer,criticize and learn.In order to provide reference for promoting the further development of network toxicology and the construction of safety evaluation of traditional Chinese medicine.
Traditional Chinese medicinetoxic mechanismsafety of traditional Chinese medicinenetwork toxicologyadverse outcome predictionomics technology
NETL
NSTL
万方数据
维普
