Pharmacological and clinical studies on treatment of vertigo by classical formula Wendan Decotion and its analogues
Wendan Decoction is a classic expectorant formula widely used in diseases of the nervous system,circulatory system,endocrine system and digestive system.Modern studies have shown that Wendan Decoction and its analogs(Jiawei Wendan Decoction,Huanglian Wendan Decoction,Chaibai Wendan Decoction)have anti-inflammatory,glycolipid metabolism regulating,antidepressant and antioxidant effects,and can treat vertigo by decreasing cellular inflammation,inhibiting the expression of free fatty acids,and promoting the expression of superoxide dismutase(SOD).The pharmacological effects of Wendan Decoction and its analogous formulas and their applications in vertigo are reviewed,with a view to providing a basis for the development of new drugs for the treatment of vertigo and the rational use of drugs in the clinic.