Progress in study of immunomodulators against Acinetobacter baumannii infections
Acinetobacter baumannii infections are of great concern because of their widespread antimicrobial resistance and high mortality.Conventional antimicrobial drug treatment strategies are not sufficiently effective.The interaction between A.baumannii and the host immune response influences the severity of infection as well as clinical regression.Improving the host immune response through immunomodulation is an effective therapeutic option.Immunomodulators have the potential to treatA.baumannii infections either alone or as immune adjuvants in combination with antimicrobials.It has emerged as a promising strategy to improve infection outcomes.New therapies based on immunomodulators has attracted much attention.In this article,the research progress of different types of drugs against A.baumannii infection(such as biological agents,immune system products,chemically synthesized preparations,traditional Chinese medicine or plant medicine ingredients)were systematically described,hoping to provide help for immunotherapy of A.baumannii infection.
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