Evaluation of clinical application of carbapenem antibiotics
Objective To analyze the clinical application of carbapenem antibiotics for special use in a hospitals,analyze and evaluate the rationality of these drugs,and promote the rational use of carbapenem antibiotics.Methods A retrospective analysis was used to collect the medical records of 364 patients receiving carbapenem antibiotics in Nanjing Hospital Affiliated to Nanjing University of Chinese Medicine from January 1,2023 to June 30,2023.The patients'age,infection site,microorganism examination,pathogen culture,drug duration,drug consultation,combined drug use and patients'prognosis after drug use were analyzed and discussed.The rationality of the drug use was evaluated.Results Most of 364 patients were aged,62.6％were treated for pulmonary infection.The rate of microbial detection before medication was 86.8％,the main pathogens were Escherichia coli and Klebsiella pneumoniae.The course of medication and the combination of medication basically met the expected target.The consultation rate is low,especially that of clinical pharmacists.The number of effective treatment cases was 311(85.4％).The incidence of adverse reactions was 1.65％,and the symptoms were mild.Conclusion The clinical application of carbapenem antibiotics in our hospital is basically reasonable,and the unreasonable situation should be further supervised to promote the rational use of carbapenems.
carbapenem antibioticsspecial use levelantibioticsclinical applicationrationality evaluation
NETL
NSTL
万方数据
