Advancements in clinical research and safety evaluation of semaglutide
As a novel glucagon-like peptide-1 receptor agonist(GLP-1RA),semaglutide is utilized domestically for the treatment of type 2 diabetes mellitus(T2DM).Its unique pharmacological characteristics endow it with significant effects in blood glucose control,weight management,and improvement of insulin resistance.Recent clinical research further reveals its potential in reducing cardiovascular events,non-alcoholic fatty liver disease,cancer immunotherapy,and neurodegenerative diseases.However,the use of semaglutide is also accompanied by some new risks,such as concerns related to gallbladder diseases and delayed gastric emptying.This article summarizes the latest research findings,comprehensively assessing the efficacy and safety of semaglutide in various fields,with the aim of providing guidance for its broader clinical application.
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