Research progress on animal models of functional dyspepsia in traditional Chinese medicine syndromes and evaluation indicators
Functional dyspepsia(FD),as a functional gastrointestinal disease,is treated in traditional Chinese medicine through a combination of symptoms and symptoms.FD is divided into spleen deficiency and qi stagnation syndrome,liver stomach disharmony syndrome,spleen stomach damp heat syndrome,spleen stomach deficiency and cold syndrome,mixed cold and heat syndrome,liver depression and spleen deficiency syndrome,and liver depression and qi stagnation syndrome.The construction of FD animal models is based on the specific pathogenesis of syndrome types to simulate human FD symptoms,and detection indicators often use behavioral,gastrointestinal dynamics,and related protein levels to evaluate the similarity between the model and FD patients.Animal models that meet the symptoms are the prerequisite and foundation for conducting pharmacological research and evaluation.The modeling methods and detection indicators of traditional Chinese medicine syndrome types in FD are currently organized and analyzed,aiming to improve and optimize the FD animal model and provide support for subsequent drug research.
functional dyspepsiaanimal modelstraditional Chinese medicine syndrome typescombination of disease and syndromeevaluating indicator