Research advances on pharmacologic effects in respiratory system of extract,magnolol and honokiol from Magnoliae Officinalis Cortex
Magnoliae Officinalis Cortex has antitussive and expectorant effects,and dual-directional action on contraction and relaxation of bronchial smooth muscle.Magnolol and honokiol are hydrophotic isomer of propenyl biphenol-type structure,and major active components of Magnoliae Officinalis Cortex in pharmacologic action of respiratory system.Magnolol and honokiol have relaxation of trachea smooth muscle and antiasthmatic effect,have lung-protection,and antagonize lung injury induced by various pathological factors.Magnolol and honokiol have broad-spectrum antibacterial and anti-viral effects,and cellular protection,too.Magnolol and honokiol to prevention and treatment for various pneumonia with basic disease were recommended,intended to be developed as a new drug for clinical use.
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