Progress on anti-tumor pharmacological effects and mechanism of alkaloids in traditional Chinese medicine of Dendrobium Sw.
Alkaloids in traditional Chinese medicine of Dendrobium Sw.are novel in structure and have diverse pharmacological effects,especially in the field of anti-cancer.Many alkaloids from traditional Chinese medicine of Dendrobium Sw.have been shown to have significant anti-cancer activities against lung cancer,gastric cancer,liver cancer,breast cancer,colon cancer,and cervical cancer,indicating great potential for the development of new drugs.However,there is still insufficient systematic analysis of their anti-cancer pharmacological effects and mechanisms,which leads to blind spots and limitations in understanding and applying Alkaloids in traditional Chinese medicine of Dendrobium Sw.This review aims to clarify the pharmacological effects of alkaloids in traditional Chinese medicine of Dendrobium Sw.on different types of cancer,including inducing tumor cell apoptosis,enhancing immune function,inhibiting tumor cell migration,and regulating the cell cycle.It also explores possible target molecules,providing valuable references and evidence for further exploration and development of alkaloids in traditional Chinese medicine of Dendrobium Sw.in the field of anti-cancer research.