Research progress in treatment of depression with traditional Chinese medicine by regulating monoamine neurotransmitters
Depression,as a mental disorder,seriously endangers the physical and mental health of patients.At present,chemical drugs are mainly used in clinical treatment of depression.These drugs mainly increase the concentration of monoamine neurotransmitters in synaptic gaps through different pathways of action,improving the symptoms of depression in patients.Depression lasts for a long period of time,although chemical drugs can have short-term therapeutic effects,adverse reactions are significant when taken for a long time.Traditional Chinese medicine has a long history and rich experience in treating mental illnesses,and is of great significance for the prevention and treatment of depression.The regulation of monoamine neurotransmitters is still the most important way to treat depression in clinical practice.This article reviews the mechanism of action of commonly used traditional Chinese medicine(Poria,Angelica Sinensis Radix,Bupleuri Radix,Paeoniae Radix Alba,Ziziphi Spinosae Semen,Atractylodis Macrocephalae Rhizoma,Polygalae Radix,Albiziae Cortex)and its compound(Xiaoyao Powder,Kaixin Powder,Chaihu Shugan Powder,Yueju Pill,Banxia Houpo Decoction)in treating depression by regulating monoamine neurotransmitters based on the basic theory of traditional Chinese medicine,in order to leverage the advantages of traditional Chinese medicine treatment and provide reference for the integrated diagnosis and treatment of depression.
traditional Chinese medicinedepressionmonoamine neurotransmittersBupleuri RadixXiaoyao Powder
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