A visualization analysis of basic and clinical research on Sishen Pill based on CiteSpace
Objective To analyze the current research status and development trends in the field of Sishen Pills studies.Methods Chinese literature on the basic and clinical research of Sishen Pills published between January 1,2000,and March 12,2024,was retrieved from CNKI,Wanfang,and VIP databases.Using bibliometric methods,the data were organized and visualized with NoteExpress V3.0 and CiteSpace 6.2.R6,and a knowledge map was created.Results A total of 128 articles on basic research and 401 articles on clinical research were included,showing a fluctuating upward trend in annual publication volume.Several research teams have formed in basic research,with the team led by Liu Duanyong being notably influential.However,no influential groups have emerged in clinical research.A large collaborative network centered around Gansu University of Chinese Medicine has formed in basic research,while clinical research institutions have yet to form significant collaborative networks.Hotspots in basic research mainly include ulcerative colitis,signaling pathways,and gut microbiota,while clinical research focuses on ulcerative colitis,clinical efficacy,and renowned experts'experiences.Conclusion At the current stage,significant achievements have been made in both the basic and clinical research of Sishen Pills.The foundational studies on Sishen Pills are progressively deepening,particularly in the areas of apoptosis,autophagy,energy metabolism,and intestinal microbiota,aiming to elucidate their regulatory mechanisms to foster broader clinical applications.
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