Determination of fifteen elements in Qinzhou export Penaeus vannamei were studied by ICP-AES after digested by HNO3 in microwave system. The determination results showed the method was sensitive and accurate. The reliability of analytical data was checked by additional standard recovery test and method precision. Recoveries of the method for these elements were in the range of 92.0%~110.0%, with the RSD≤3.83%(n=5). Compared with the commonly used single-element analytical techniques, the proposed method has the advantages of more efficient and accurate.