Clinical Value of Peripheral Blood Eosinophils Combined with Neutrophil to Lymphocyte Ratio in Diagnosis of Mycoplasma Pneumoniae Infection in Children
Objective:To investigate the clinical value of peripheral blood eosinophils(EOS)combined with neutrophil to lymphocyte ratio(NLR)in the diagnosis of Mycoplasma pneumoniae infection in children.Method:A total of 144 children with suspected Mycoplasma pneumoniae infection admitted to the Pediatric Outpatient Department of Taizhou Obstetrics and Gynecology Hospital from August 2020 to August 2022 were selected as the study objects.EOS and NLR levels in peripheral blood of the children were detected,and the children were divided into uninfected group and Mycoplasma pneumoniae infection group according to the enzyme linked immunosorbent assay results.The clinical data of the children were collected,and the risk factors of Mycoplasma pneumoniae infection in children were analyzed by logistic multivariate regression.The receiver operating characteristic curve(ROC)was prepared,and the area under the curve(AUC)was used to evaluate the value of peripheral blood EOS,NLR and combined diagnosis of Mycoplasma pneumoniae infection in children.Result:In 144 suspected children with Mycoplasma pneumoniae infection,106 cases infected were confirmed as Mycoplasma pneumoniae infection group by enzyme linked immunosorbent assay,and the remaining 38 cases uninfected were confirmed as uninfected group.There were no statistically significant in age,sex,height,weight between the two groups(P>0.05).The levels of NLR and EOS in the Mycoplasma pneumoniae infection group were higher than those in the uninfected group,and the differences were statistically significant(P<0.05).Multivariate logistic regression analysis showed that both EOS and NLR in peripheral blood were risk factors for Mycoplasma pneumoniae infection in children(P<0.05).ROC curve results showed that the AUC of EOS and NLR in peripheral blood for single and combined diagnosis of Mycoplasma pneumoniae infection in children were 0.716,0.703 and 0.809,and the AUC of combined diagnosis was higher than that of single diagnosis.Conclusion:The levels of EOS and NLR in peripheral blood of children with Mycoplasma pneumoniae infection are abnormal,and the levels of EOS and NLR are closely related to Mycoplasma pneumoniae infection in children,and they are of great value in the diagnosis of Mycoplasma pneumoniae infection in children,and the combined diagnosis of Mycoplasma pneumoniae infection in children is of higher value.
Peripheral blood eosinophilNeutrophil to lymphocyte ratioMycoplasma pneumoniae infection in childrenClinical value
万方数据
维普
