Prognostic Value of Serum ET and Electrocardiogram T Wave in Death of Patients with External Traumatic Cerebral Hemorrhage
Objective:To investigate the predictive value of serum endothelin(ET)and electrocardiogram T wave in death of patients with external traumatic cerebral hemorrhage.Method:The clinical data of 102 patients with external traumatic cerebral hemorrhage admitted to Suzhou BenQ Hospital Affiliated to Nanjing Medical University from March 2017 to May 2022 were retrospectively analyzed.After 12 months of postoperative follow-up,the patients with external traumatic cerebral hemorrhage were divided into death group(n=12)and survival group(n=90)according to the death situation.The general data,serum ET and electrocardiogram T wave changes of the two groups were compared,and the relationship between serum ET,electrocardiogram T wave and other clinical factors and the death of the patients with external traumatic cerebral hemorrhage was analyzed by logistic regression analysis.The predictive value of serum ET and electrocardiogram T wave in death of patients with external traumatic cerebral hemorrhage was analyzed by reference to receiver operating characteristic(ROC)curve and area under curve(AUC).Result:After 12 months of follow-up,there were 12 deaths among 102 patients with exceptional traumatic cerebral hemorrhage,with an incidence of 11.76%(12/102).There was no significant difference in gender,body mass index(BMI),smoking history and serum creatinine(Cr)between the two groups(P>0.05).Age,ET level,electrocardiogram T wave inversion ratio and hematoma volume in the death group were higher than those in the survival group,and the differences were statistically significant(P<0.05).Multivariate logistic regression analysis showed that age,ET level,electrocardiogram T wave inversion and hematoma volume were all risk factors for death in patients with external traumatic cerebral hemorrhage(P<0.05).ROC curve results showed that the AUC of serum ET combined with electrocardiogram T wave in predicting the risk of death in patients with external traumatic cerebral hemorrhage was 0.904,which was higher than 0.773 and 0.771 of serum ET and electrocardiogram T wave alone(P<0.05).Conclusion:Age,serum ET level,electrocardiogram T wave inversion and hematoma volume are all risk factors for death in patients with external traumatic cerebral hemorrhage.The combination of serum ET and electrocardiogram T wave change has a high predictive value for death in patients with external traumatic cerebral hemorrhage.
EndothelinElectrocardiogram T wave changesExternal traumatic cerebral hemorrhage
万方数据
维普
