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老年早期肺癌患者应用胸腔镜肺叶切除术的效果及安全性

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目的:探究老年早期肺癌患者应用胸腔镜肺叶切除术的效果和手术安全性。方法:选择 2020 年 3 月—2023 年3 月泗洪中信医院胸外科收治的 76 例老年早期肺癌患者作为研究对象。根据计算机随机编号分为对照组与试验组,各 38 例。对照组实施常规开胸手术,试验组行胸腔镜肺叶切除术。比较两组围手术期相关指标、炎症指标、术后并发症发生情况。结果:试验组引流时间、手术时间、住院时间短于对照组,视觉模拟评分法(VAS)评分低于对照组,术中出血量少于对照组,差异有统计学意义(P<0。05)。术前,两组C反应蛋白(CRP)、前清蛋白(PA)、白细胞介素-6(IL-6)比较,差异无统计学意义(P>0。05);术后 1 d,两组CRP、IL-6 高于术前,PA低于术前,但试验组CRP、IL-6 低于对照组,PA高于对照组,差异有统计学意义(P<0。05)。试验组并发症发生率为 2。63%,显著低于对照组的 15。79%,差异有统计学意义(P<0。05)。结论:同常规开胸手术相比,老年早期肺癌患者应用胸腔镜肺叶切除术的效果显著,可以显著缩短引流时间、住院时间,降低炎症水平和术后疼痛程度,术后安全性良好。
Efficacy and Safety of Thoracoscopic Pulmonary Lobectomy in Elderly Patients with Early Stage of Lung Cancer
Objective:To explore the efficacy and safety of thoracoscopic pulmonary lobectomy in elderly patients with early stage of lung cancer.Method:A total of 76 elderly patients with early stage of lung cancer admitted to the Thoracic Surgery Department of CITIC Hospital,Sihong County from March 2020 to March 2023 were selected as the study objects.According to the computer random number,they were divided into control group and experimental group,with 38 cases in each group.The control group underwent conventional thoracotomy,and the experimental group underwent thoracoscopic pulmonary lobectomy.The perioperative related indexes,inflammatory indexes and postoperative complications were compared between the two groups.Result:The drainage time,surgery time and hospital stay of the experimental group were shorter than those of the control group,the visual analogue scale(VAS)score was lower than that of the control group,and the intraoperative blood loss was less than that of the control group,the differences were statistically significant(P<0.05).Before surgery,there were no significant differences in C-reactive protein(CRP),prealbumin(PA)and interleukin-6(IL-6)between the two groups(P>0.05).At 1 d after surgery,CRP and IL-6 were higher than those before surgery,PA were lower than those before surgery,but CRP and IL-6 in experimental group were lower than those in control group,PA was higher than that in control group,the differences were statistically significant(P<0.05).The complication rate of experimental group was 2.63%,which was significantly lower than 15.79%of control group,and the difference was statistically significant(P<0.05).Conclusion:Compared with conventional thoracotomy,the application of thoracoscopic pulmonary lobectomy in elderly patients with early stage of lung cancer has significant effects,which can significantly shorten the drainage time,hospital stay,reduce the level of inflammation and postoperative pain,and have good postoperative safety.

Early stage of lung cancerThoracoscopyPulmonary lobectomyComplicationsHospital stay

韩旭、崔进才、陈翘楚

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泗洪中信医院 江苏 泗洪 223900

早期肺癌 胸腔镜 肺叶切除术 并发症 住院时间

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(2)
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