Effect of Transfusion of Washed Red Blood Cells and Removing White Suspended Red Blood Cells in the Treatment of Autoimmune Hemolytic Anemia
Objective:To investigate the effect of transfusion of washed red blood cells and removing white suspended red blood cells in the treatment of autoimmune hemolytic anemia(AIHA).Method:Sixty-four AIHA patients admitted to the First Affiliated Hospital of Bengbu Medical College from March 2020 to March 2023 were retrospectively selected as the study objects.According to the different treatment methods,they were divided into experimental group and control group,32 cases in each group.The control group was transfused with removing white suspended red blood cells and the experimental group was transfused with washed red blood cells.The clinical efficacy 24 h after blood transfusion,relevant indexes before and 24 h after blood transfusion,and transfusion reaction were compared between the two groups.Result:The total effective rate of experimental group was higher than that of control group,and the difference was statistically significant(P<0.05).At 24 h after blood transfusion,hemoglobin(Hb)and red blood cell count(RBC)were increased,reticulocyte percentage(Ret)and total bilirubin(TBIL)levels were decreased,and Hb and RBC in experimental group were higher than those in control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of blood transfusion reaction between the two groups(x2=1.016,P>0.05).Conclusion:For AIHA patients,compared with transfusions of removing white suspended red blood cells,transfusions of washed red blood cells have a higher overall effective rate in transfusion therapy,and the effect is more obvious in the improvement of Hb and RBC.
Autoimmune hemolytic anemiaWashed red blood cellsBlood transfusion