Distribution and Drug Resistance Analysis of Pathogenic Bacteria in ICU Infection
Objective:To analyze the distribution and drug resistance of pathogenic bacteria in Intensive Care Unit(ICU)infection.Method:The case data of 120 ICU patients in Funing County People's Hospital from December 2019 to December 2022 were retrospectively analyzed.The incidence of nosocomial infection in ICU patients and the distribution characteristics of pathogenic bacteria were analyzed,and the drug resistance of nosocomial infection patients in ICU was analyzed.Result:Nosocomial infection occurred in 30 of 120 ICU patients,and the incidence of nosocomial infection was 25.00%.A total of 35 strains were detected in 120 patients with nosocomial infection in ICU,of which 20 were Gram-negative bacteria,accounting for 57.14%of the total number of pathogens,12 were Gram-positive bacteria,accounting for 34.29%of the total number of pathogens,and 3 were fungi,accounting for 8.57%of the total number of pathogens.The drug resistance of Klebsiella pneumoniae and Escherichia coli was analyzed.The drug resistance rates of Klebsiella pneumoniae to Cefazolin,Levofloxacin and Cefepime were all>50.00%.The resistance rate of Klebsiella pneumoniae to Imipenem and Erythromycin was the lowest,was 20.00%,and the resistance rate of Cefazolin was the highest,was 100.00%.The resistance rates of Escherichia coli to Ampicillin and Moxifloxacin were≥50.00%.The resistance rate of Escherichia coli to Imipenem was the lowest,was 0,and the resistance rate of Ampicillin was the highest,was 75.00%.The drug resistance of Staphylococcus aureus and Staphylococcus epidermidis was analyzed.The resistance rates of Staphylococcus aureus to Ampicillin,Levofloxacin and Erythromycin were all>50.00%.The resistance rates of Staphylococcus epidermidis to Ampicillin and Erythromycin were 100.00%.The resistance rate of Staphylococcus aureus to Moxifloxacin was 0.The resistance rate of Staphylococcus epidermidis to Rifampicin was 0.Conclusion:Gram-negative bacteria were the main pathogens detected in ICU patients,and most of the pathogens had different degrees of drug resistance,rational drug use should be targeted according to the results of drug sensitivity in clinical treatment.
Intensive Care UnitNosocomial infectionDistribution of pathogenic bacteriaDrug resistanceStaphylococcus aureusStaphylococcus epidermidis
万方数据
维普
