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头孢唑肟钠联合复方芩兰口服液治疗小儿肺炎的临床效果

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目的:探讨头孢唑肟钠联合复方芩兰口服液治疗小儿肺炎的临床效果。方法:选取 2022 年 2 月—2023 年 2 月周口市第一人民医院收治的 120 例小儿肺炎患儿作为研究对象,根据随机数表法将患儿分为对照组和观察组,各 60 例。对照组给予头孢唑肟钠治疗,观察组给予头孢唑肟钠联合复方芩兰口服液治疗。比较两组治疗前后体液免疫指标[免疫球蛋白G(IgG)、免疫球蛋白A(IgA)、免疫球蛋白M(IgM)]、炎症因子[C反应蛋白(CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]、临床疗效及不良反应发生情况等。结果:两组治疗前体液免疫指标、炎症因子比较,差异无统计学意义(P>0。05);观察组治疗 1 周后IgG水平高于对照组,IgA、IgM、CRP、IL-6、TNF-α水平均低于对照组,差异有统计学意义(P<0。05)。治疗 1 周后,观察组临床总有效率为 93。33%,高于对照组的 78。33%,不良反应发生率为 3。33%,低于对照组的 16。67%,差异有统计学意义(P<0。05)。结论:头孢唑肟钠联合复方芩兰口服液治疗小儿肺炎的临床效果显著,能增强机体免疫功能,减低了炎症反应与不良反应发生率。
Clinical Effect of Ceftizoxime Sodium Combined with Fufangqinlan Koufuye in the Treatment of Pediatric Pneumonia
Objective:To explore the clinical effect of Ceftizoxime Sodium combined with Fufangqinlan Koufuye in the treatment of pediatric pneumonia.Method:A total of 120 children with pediatric pneumonia who admitted to Zhoukou First People's Hospital from February 2022 to February 2023 were selected as the research objects,the children were divided into control group and observation group according to the random number table method,with 60 cases in each group.The control group was treated with Ceftizoxime Sodium,and the observation group was treated with Ceftizoxime Sodium combined with Fufangqinlan Koufuye.The humoral immune indexes[immunoglobulin G(IgG),immunoglobulin A(IgA),immunoglobulin M(IgM)],inflammatory factors[C-reactive protein(CRP),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)]before and after treatment,clinical efficacy and adverse reactions were compared between two groups.Result:There were no significant differences in humoral immune indexes and inflammatory factors between two groups before treatment(P>0.05);the level of IgG in the observation group after 1 week of treatment was higher than that in the control group,and the levels of IgA,IgM,CRP,IL-6 and TNF-α were lower than those in the control group,the differences were statistically significant(P<0.05).After 1 week of treatment,the total clinical effective rate of the observation group was 93.33%,which was higher than 78.33%of the control group,and the incidence of adverse reactions was 3.33%,which was lower than 16.67%of the control group,the differences were statistically significant(P<0.05).Conclusion:The clinical effect of Ceftizoxime Sodium combined with Fufangqinlan Koufuye in the treatment of pediatric pneumonia is significant,which can enhance the immune function of body,reduce the inflammatory response and the incidence of adverse reactions.

Ceftizoxime SodiumFufangqinlan KoufuyePediatric pneumoniaImmune indexes

吴娜

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周口市第一人民医院 河南 周口 466700

头孢唑肟钠 复方岑兰口服液 小儿肺炎 免疫指标

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(3)
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