Effect of Shenqi Jiangtang Capsules Combined with Insulin Detemir in the Treatment of Incipient Type 2 Diabetes with Obesity
Objective:To investigate the clinical effect of Shenqi Jiangtang Capsules combined with Insulin Detemir in the treatment of incipient type 2 diabetes with obesity.Method:A total of 100 patients with incipient type 2 diabetes with obesity treated in the 960th Hospital of the People's Liberation Army of China from June 2020 to June 2022 were selected as the study objects,and they were divided into control group(n=50)and study group(n=50)according to random stratification method.The control group was treated with Insulin Detemir,and the study group was treated with Shenqi Jiangtang Capsules on the basis of the control group.Blood glucose level,islet function index level,blood lipid level,body mass index(BMI)before and after medication,blood glucose standard time were compared between the two groups.Result:The levels of fasting plasma glucose(FPG),2 h postprandial blood glucose(2 h PG)and glycosylated hemoglobin(HbA1c)in the two groups after medication were significantly lower than those before medication,and the levels in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).After medication,insulin resistance index(HOMA-IR)in both groups were lower than those before medication,and that in the study group was lower than that in the control group,insulin beta cell function(HOMA-β)and fasting insulin(FINS)levels in both groups were higher than those before medication,and those in the study group were higher than those in the control group,the differences were statistically significant(P<0.05).After medication,the levels of triglyceride(TG),low-density lipoprotein cholesterol(LDL-C)and total cholesterol(TC)in both groups were lower than those before medication,those in the study group were lower than those in the control group,and the levels of high density lipoprotein cholesterol(HDL-C)in both groups were higher than before medication,that in the study group was higher than that in the control group,and the differences were statistically significant(P<0.05).BMI of both groups decreased after medication,and that in the study group was lower than that in the control group,the differences were statistically significant(P<0.05).The blood glucose standard time of the study group was shorter than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:Shenqi Jiangtang Capsules combined with Insulin Detemir not only can effectively stabilize the blood glucose and lipid levels of patients with incipient type 2 diabetes and obesity,but also reduce body weight and improve islet function.
Incipient type 2 diabetesObesityShenqi Jiangtang CapsulsesInsulin DetemirBlood glucose
万方数据
维普
