Correlation between Expression Levels of Serum Ca,P,iPTH and HbA1c and Prognosis of Patients with Diabetic Kidney Disease Undergoing Hemodialysis
Objective:To analyze the correlation between expression levels of serum calcium(Ca),phosphorus(P),intact parathyroid hormone(iPTH)and glycosylated hemoglobin(HbA1c)and prognosis of patients with diabetic kidney disease(DKD)undergoing hemodialysis.Method:The clinical data of 83 patients with DKD who underwent hemodialysis in Shijingshan Teaching Hospital of Capital Medical University were retrospectively analyzed from January 2020 to December 2021.According to the unplanned readmission status of patients within 1 year of follow-up,they were divided into poor prognosis group(n=21)and good prognosis group(n=62).The levels of serum Ca,P,iPTH and HbA1c were compared between the two groups before dialysis,and the correlation between levels of serum Ca,P,iPTH and HbA1c and prognosis of patients with DKD undergoing hemodialysis were analyzed.Receiver operating characteristic(ROC)curve was used to evaluate the predictive value of levels of serum were analyzed P,iPTH and HbA1c on the prognosis of DKD.Result:The levels of serum P and iPTH of patients in good prognosis group were higher than those in poor prognosis group,while the HbA1c level was lower than that in poor prognosis group,the differences were statistically significant(P<0.05).Multivariate logistic regression analysis showed the levels of serum P and iPTH and HbA1c were influencing factors of patients with DKD undergoing hemodialysis(P<0.05).ROC results showed that the AUC values of serum P,iPTH and HbA1c were 0.659,0.871 and 0.855 respectively in the predictive of prognosis of patients with DKD undergoing hemodialysis,with high predictive value.Conclusion:The prognosis of patients with DKD undergoing hemodialysis is related to the expression of serum P,iPTH and HbA1c.Clinically,the serum P,iPTH and HbA1c levels of DKD hemodialysis patients can be detected to predict the prognosis,and active intervention can be conducted to improve the prognosis of patients with poor prognosis.
万方数据
维普
