Effect of Lung Wedge Resection under Thoracoscopy in Elderly Lung Cancer Patients and Its Influence on Respiratory Function and Stress Indicators
Objective:To explore the effect of lung wedge resection under thoracoscopy in elderly lung cancer patients and its influence on respiratory function and stress indicators.Method:A total of 102 elderly patients with lung cancer admitted to Wuxi Second People's Hospital from January 2020 to January 2023 were selected,they were randomly divided into two groups by random number table method.The study group(n=51)was treated with lung wedge resection under thoracoscopy,and the control group(n=51)was treated with routine lobectomy under thoracoscopy,The perioperative indicators(operation time,intraoperative bleeding,chest drainage tube indwelling time,drainage flow,hospital stay),respiratory function indicators such as forced expiratory volume in one second(FEV1),one second rate[FEV1/forced vital capacity(FVC)%],peak expiratory flow(PEF),stress indicators[cortisol(Cor),norepinephrine(NE),angiotensin Ⅱ(AT-Ⅱ),serum amyloid A(SAA)],complications(incision infection,lung leakage,chylothorax)were compared between the two groups.Result:The placement time and hospitalization time of the thoracic drainage tube in the study group were shorter than those in the control group,the intraoperative bleeding volume and drainage volume were lower than those in the control group,the differences were statistically significant(P<0.05).There was no statistically significant difference in surgical time between the two groups(P>0.05).Three months after surgery,FEV1,FEV1/FVC%and PEF in both groups were lower,but FEV1,FEV1/FVC%and PEF in the study group were higher than those in the control group,the differences were statistically significant(P<0.05).Immediately after surgery,the levels of Cor,NE,AT-Ⅱ,and SAA in both groups increased with statistical significance,but the levels of Cor,NE,AT-Ⅱ,and SAA in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).The incidence of complications in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Lung wedge resection under thoracoscopy in elderly patients with lung cancer can obtain better curative effect,and has less impact on stress level,reduce the degree of postoperative lung function injury and postoperative complications.
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