首页|阿尔茨海默病治疗的研究进展

阿尔茨海默病治疗的研究进展

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阿尔茨海默病(AD)主要发生在老年人身上,是一种具有起病隐匿、渐进性加重特点的脑中枢神经系统功能退行性疾病,其临床表现主要为认知功能下降,出现记忆障碍、行为障碍,且伴有一系列精神症状的出现.随着全球老龄化人口的增多,AD发病率也在逐渐升高,严重威胁人类的生命健康.由于其发病原因复杂,目前尚无定性机制,缺少理想治疗途径.近年来,Tau蛋白磷酸化、胆碱能假说等研究的加速和深入为AD治疗提供了新的策略,尤其是AD的临床试验进程越来越受到人们的关注,本文拟通过对近些年AD治疗的相关文献进行简要综述,为AD的治疗提供一些思路和参考.
Research Progress in the Treatment of Alzheimer's Disease
Alzheimer's disease(AD),which mainly occurs in the elderly,which is a degenerative disease of central nervous system function with hidden onset and progressive aggravation.Its clinical manifestations are mainly cognitive decline,memory impairment and behavior disorder,and a series of mental symptoms.With the increase of the global aging population,the incidence of AD is gradually increasing,which seriously threatens human life and health.Due to the complexity of its pathogenesis,there is no qualitative mechanism and no ideal treatment.In recent years,the acceleration and deepening of research on Tau protein phosphorylation and cholinergic hypothesis have provided new strategies for the treatment of AD,especially the clinical trial process of AD has attracted more and more attention.This paper intends to provide some ideas and references for the treatment of AD through a brief review of relevant literature on the treatment of AD in recent years.

Alzheimer's diseaseClinical medicationsNon-pharmacological treatments

罗翀、段娜娜、梁初霖、黄可雄、张胜喻、谭洁

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桂林医学院医学检验学院 广西 桂林 541004

桂林医学院研究生学院

阿尔茨海默病 临床药物 非药物治疗

2019年国家级大学生创新创业训练计划项目

201910601041

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(4)
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