Effects of Right Ventricular Septal Pacing on Myocardial Injury,Cardiac Function and Left Ventricular Systolic Function in Patients with Permanent Cardiac Pacemaker Implantation
Objective:To explore the effects of right ventricular septal pacing on myocardial injury,cardiac function and left ventricular systolic function in patients with permanent cardiac pacemaker implantation.Method:A total of 80 patients undergoing permanent cardiac pacemaker implantation in Qingyuan People's Hospital from January 2019 to January 2021 were selected.According to the computer grouping method,the patients were divided into apical group(pacing site at the apical)and septal group(pacing site at the right ventricular septal),80 cases in each group.Myocardial injury,cardiac function,left ventricular systolic function,synchrony and complications were observed in both groups.Result:After operation,the levels of N-terminal brain natriuretic peptide precursor(NT-proBNP)and creatine kinase isoenzyme(CK-MB)in two groups were lower than before operation,and the levels of NT-proBNP and CK-MB in the septal group were lower than those in the apical group,the differences were statistically significant(P<0.05).After operation,the cardiac output(CO),left ventricular ejection fraction(LVEF)and left ventricular end-diastolic diameter(LVEDD)in both groups were lower than before operation,and the CO,LVEF and LVEDD in septal group were higher than those in apical group,the differences were statistically significant(P<0.05).After operation,end-systolic left ventricular volume(LVESV),end-diastolic left ventricular volume(LVEDV),the standard deviation of 18-segment peak time(Tp-SD)and QRS were higher than those before operation,the LVESV and LVEDV of the septal group were higher than those of the apical group,Tp-SD and QRS were lower than those of the apical group,the differences were statistically significant(P<0.05).The total incidence of complications in the septal group was 7.50%,which was not statistically significant compared with 12.50%in the apical group(P>0.05).Conclusion:Compared with apical pacing,right ventricular septal pacing can reduce myocardial injury and influence on cardiac function in patients with implanted permanent cardiac pacemaker,improve left ventricular systolic function and synchronization,and do not increase the occurrence of complications.
国家科技期刊平台
NSTL
万方数据
