首页|针灸对缺血性脑卒中后面瘫患者中医症状体征评分及凝血功能的影响

针灸对缺血性脑卒中后面瘫患者中医症状体征评分及凝血功能的影响

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目的:探究针灸对缺血性脑卒中后面瘫患者中医症状体征评分及凝血功能的影响。方法:前瞻性选取 2019 年10 月—2022 年 10 月苏州大学附属张家港医院收治的 60 例缺血性脑卒中后面瘫患者为研究对象。根据随机数表法将其分为研究组和对照组,各 30 例。对照组给予常规面部肌群康复训练,研究组在对照组的基础上给予针灸治疗。比较两组临床疗效,治疗前后中医症状体征评分、House-Brackmann(H-B)分级、凝血功能、相关指标。结果:研究组总有效率显著高于对照组,差异有统计学意义(P<0。05)。治疗后,两组口角喁斜、面部表情、眼裂闭合、额纹消失、鼻唇沟深浅、口渴心烦评分及总分均低于治疗前,研究组口角喁斜、额纹消失、口渴心烦评分及总分均低于对照组,差异有统计学意义(P<0。05)。治疗后,研究组Ⅰ级占比显著高于对照组,差异有统计学意义(P<0。05)。治疗后,两组K值、R值均降低,MA值升高,研究组K值、R值均低于对照组,MA值高于对照组,差异有统计学意义(P<0。05)。治疗后,两组Toll样受体 4(TLR4)、核转录因子κB(NF-κB)p65 蛋白水平均降低,研究组TLR4、NF-κB p65 蛋白水平均低于对照组,差异有统计学意义(P<0。05)。结论:针灸治疗缺血性脑卒中后面瘫有显著效果,能有效改善患者症状体征和凝血功能,能够提高患者面部功能。
Influence of Acupuncture on Traditional Chinese Medical Symptom and Sign Score and Coagulation Function of Facial Palsy Patients after Ischemic Stroke
Objective:To explore the influence of acupuncture on traditional Chinese medical symptom and sign score and coagulation function of facial palsy patients after ischemic stroke.Method:A total of 60 facial palsy patients after ischemic stroke admitted to Zhangjiagang Hospital Affiliated to Soochow University from October 2019 to October 2022 were prospectively selected as the study objects.According to random number table method,they were divided into study group and control group,30 cases in each group.The control group was given routine facial muscle group rehabilitation training,and the study group was given acupuncture treatment on the basis of the control group.The clinical efficacy,traditional Chinese medical symptom and sign scores,House-Brackmann(H-B)grading,coagulation function before and after treatment and related indexes were compared between the two group.Result:The total effective rate of the study group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,slanted mouth,facial expression,eye fissure closure,frontal striae disappearance,nasolabial groove depth,thirst upset scores and total score of both groups were lower than those before treatment,and the slanted mouth,facial expression,thirst upset scores and total score of the study group were lower than those of the control group,and the differences were statistically significant(P<0.05).After treatment,the proportion of grade Ⅰ in the study group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).After treatment,K value and R value of both groups decreased,MA value increased,K value and R value in the study group were lower than those in the control group,MA value was higher than that in the control group,the differences were statistically significant(P<0.05).After treatment,the levels of toll-like receptor 4(TLR4)and nuclear transcription factor κB(NF-κB)p65 protein were decreased in both groups,and the levels of TLR4 and NF-κB p65 protein in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Acupuncture have significant effect on facial palsy after ischemic stroke,which can effectively improve the symptoms,signs and coagulation function of patients,and improve the facial function of patients.

StrokeAcupunctureFacial palsyTraditional Chinese medicine symptom and sign scoreCoagulation function

张金媛、葛玲玲、顾银银、丁瑛骅

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苏州大学附属张家港医院 江苏 张家港 215600

脑卒中 针灸 面瘫 中医症状体征评分 凝血功能

张家港市科技支撑计划社会发展项目

ZKS1943

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(6)
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