Effects of Different Administration Method of Oxytocin on Parturients in Cesarean Section
Objective:To observe the effects of different administration method of Oxytocin on parturients undergoing cesarean section.Method:A total of 216 parturients undergoing cesarean section in Xinglin Branch of the First Affiliated Hospital of Xiamen University from February 2021 to February 2023 were selected as the study objects.They were randomly divided into group A,group B and group C,with 72 cases in each group.Cesarean section was performed in all three groups,group A was given uterus intramuscular injection of Oxytocin,group B was given intravenous infusion of Oxytocin,and group C was given intravenous infusion+Murphy's dropper uterus of Oxytocin.Postpartum hemorrhage condition,hemodynamic indexes before and 10 min after medication,inflammatory factors before and 24 h after surgery,and adverse reactions were compared among the three groups.Result:The incidence of postpartum hemorrhage and amount of postpartum hemorrhage in group C were lower than those in group A and group B,and the differences were statistically significant(P<0.05).At 10 min after medication,systolic blood pressure,diastolic blood pressure,heart rate,cardiac output(CO)and cardiac index(CI),and mean arterial pressure(MAP)of the C group were higher than those of group A and group B,and the differences were statistically significant(P<0.05).At 24 h after surgery,the levels of tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)in group C were lower than those in group A and group B,and the levels of interleukin-4(interleukin-4)and interleukin-10(IL-10)were higher than those in group A and group B,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions among the three groups(P>0.05).Conclusion:Intravenous infusion+Murphy's dropper uterus of Oxytocin can reduce the amount of postpartum bleeding and the rate of postpartum bleeding in parturients with cesarean section,improve the hemodynamics.
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