首页|气囊扩张术与ERCP联合应用对胆总管结石患者手术效果及并发症的影响

气囊扩张术与ERCP联合应用对胆总管结石患者手术效果及并发症的影响

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目的:探讨气囊扩张术与内镜逆行胰胆管造影(ERCP)联合应用对胆总管结石患者手术效果及并发症的影响。方法:选择 2021 年 2 月—2022 年 12 月泰州市人民医院消化内科收治的 94 例胆总管结石患者作为研究对象,根据随机数表法分为对照组和观察组,各 47 例。对照组采用ERCP联合内镜十二指肠乳头括约肌切开术(EST)取石治疗,观察组采用ERCP联合气囊扩张术取石治疗。比较两组肠道微生态、括约肌功能、手术指标及并发症发生率。结果:治疗后,两组双歧杆菌、乳酸杆菌高于治疗前,大肠杆菌、梭菌、拟杆菌低于治疗前,且观察组双歧杆菌、乳酸杆菌高于对照组,大肠杆菌、梭菌、拟杆菌低于对照组,差异有统计学意义(P<0。05)。治疗后,两组胆总管压力比较,差异无统计学意义(P>0。05);治疗后,观察组括约肌基础压、括约肌收缩压高峰值、括约肌收缩频率均低于对照组,差异有统计学意义(P<0。05)。观察组手术时间、黄疸消退时间、腹痛缓解时间、术后卧床时间、住院时间均显著短于对照组,差异有统计学意义(P<0。05)。观察组不良反应总发生率显著低于对照组,差异有统计学意义(P<0。05)。结论:气囊扩张术联合ERCP能够有改善胆总管结石患者的括约肌功能及手术指标,并减少并发症的发生。
Effects of Balloon Dilation Combined with ERCP on Surgery Effect and Complications in Patients with Choledocholithiasis
Objective:To investigate the effect of balloon dilation combined with endoscopic retrograde cholangiopancreatography(ERCP)on the surgery effect and complications of patients with choledocholithiasis.Method:A total of 94 patients with choledocholithiasis admitted to the Department of Gastroenterology of Taizhou People's Hospital from February 2021 to December 2022 were selected as the study objects,and they were divided into control group and observation group according to random number table method,with 47 cases in each group.The control group was treated with ERCP combined with endoscopic sphincterotomy(EST),and the observation group was treated with ERCP combined with balloon dilation.Intestinal microecology,sphincter function,surgical indexes and complication rate were compared between the two groups.Result:After treatment,Bifidobacteria and Lactobacillus were higher than those before treatment,Escherichia coli,Clostridium and Bacteroides were lower than those before treatment,and Bifidobacteria and Lactobacillus in observation group were higher than those in control group,Escherichia coli,Clostridium and Bacteroides were lower than those in control group,the differences were statistically significant(P<0.05).After treatment,there was no significant difference in common bile duct pressure between the two groups(P>0.05).After treatment,the sphincter base pressure,peak sphincter systolic pressure and sphincter contraction frequency in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).The operation time,jaundice resolution time,abdominal pain relief time,postoperative bed time and hospital stay in the observation group were significantly shorter than those in the control group,the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the observation group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:Balloon dilation combined with ERCP can improve the sphincter function and surgical indicators in patients with choledocholithiasis,and reduce the incidence of complications.

Balloon dilationEndoscopic retrograde cholangiopancreatographyCholedocholithiasisIntestinal microecologySphincter functionComplication

刘荣泉、季云、张杰

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泰州市人民医院 江苏 泰州 225300

气囊扩张术 内镜逆行胰胆管造影 胆总管结石 肠道微生态 括约肌功能 并发症

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(6)
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