Effect of Sufentanil PCIA Combined with Esketamine on Pain and Fatigue Levels in Patients Undergoing Thoracoscopic Radical Resection of Lung Cancer
Objective:To observe the effects of Sufentanil patient-controlled intravenous analgesia(PCIA)combined with Esketamine on pain and fatigue levels in patients undergoing thoracoscopic radical resection for lung cancer.Method:A total of 82 patients with lung cancer admitted to the First Hospital of Putian City from April 2022 to April 2023 were selected as the study objects and randomly divided into two groups,with 41 cases in each group.The control group was given Sufentanil PCIA,and the observation group was given Sufentanil PCIA combined with Esketamine.The pain score,fatigue score at different time points and postoperative adverse reactions were compared between the two groups.Result:At 24 h,48 h and 72 h after operation,visual analogue scale(VAS)score,identity-consequence fatigue scale(ICFS)score in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).There were no significant differences in the incidence of dizziness and lethargy between the two groups(P>0.05).The incidence of nausea,vomiting and pruritus in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion:Sufentanil PCIA combined with Esketamine can relieve postoperative pain,improve postoperative fatigue,and reduce postoperative adverse reactions in patients undergoing thoracoscopic radical resection for lung cancer surgery,with higher safety.
Thoracoscopic radical resection for lung cancerSufentanilEsketaminePatients controlled intravenous analgesiaFatigue