摘要
目的:探讨CT能谱参数对结直肠癌(CRC)病理类型鉴别的价值.方法:选取 2022 年 2 月—2023 年 2 月松滋市人民医院收治的 64 例CRC患者,所有患者均于术前 1 周进行CT能谱增强扫描.其中黏液腺癌 36 例,管状腺癌 28 例,比较不同病理类型动脉期和静脉期的碘浓度(IC)、标准化碘浓度(NIC)、碘图CT值(Overlay值)、能谱曲线斜率(λHU),分析上述CT能谱参数对CRC患者病理类型鉴别的价值.结果:黏液腺癌的动静脉期IC、Overlay值、λHU和动脉期NIC与管状腺癌相比更低,差异有统计学意义(P<0.05),两种病理类型的静脉期NIC比较,差异无统计学意义(P>0.05);logistic多因素回归分析结果显示,动脉期IC(OR=1.321)、动脉期NIC(OR=1.443)、动脉期Overlay值(OR=1.398)、动脉期λHU(OR=1.257)、静脉期IC(OR=1.520)、静脉期Overlay值(OR=1.406)、静脉期λHU(OR=1.411)是CRC患者病理类型为管状腺癌的独立危险因素(P<0.05);绘制受试者工作特征(ROC)曲线显示,动脉期IC、动脉期NIC、动脉期Overlay值、动脉期λHU、静脉期IC、静脉期Overlay值、静脉期λHU鉴别CRC患者病理类型的曲线下面积分别为 0.888、0.820、0.769、0.832、0.863、0.810、0.723.结论:不同病理类型CRC患者的动静脉期IC、Overlay值、λHU和动脉期NIC存在显著差异,上述CT能谱参数可为病理类型鉴别提供客观参考依据.
Abstract
Objective:To explore the value of CT energy spectrum parameters in distinguishing pathological types of colorectal cancer(CRC).Method:A total of 64 CRC patients admitted to Songzi People's Hospital from February 2022 to February 2023 were selected.All patients underwent CT energy spectrum enhanced scan at 1 week before surgery.There were 36 cases of mucinous adenocarcinoma and 28 cases of tubular adenocarcinoma.The iodine concentration(IC),standardized iodine concentration(NIC),iodine Overlay value(Overlay value)and energy spectrum curve slope(λHU)of different pathological types in arterial phase and venous phase were compared,and the value of the above CT spectrum parameters in the identification of pathological types of CRC patients was analyzed.Result:IC,Overlay value,λHU in arterial phase and venous phase and NIC in arterial phase of mucinous adenocarcinoma were lower than those in tubular adenocarcinoma,and the differences were statistically significant(P<0.05),there was no significant difference between the two pathological types of NIC in venous phase(P>0.05).logistic multivariate regression analysis results showed that,arterial phase IC(OR=1.321),arterial phase NIC(OR=1.443),arterial phase Overlay value(OR=1.398),arterial phase λHU(OR=1.257),venous phase IC(OR=1.520),venous phase Overlay value(OR=1.406),venous phase λHU(OR= 1.411)were independent risk factors for tubular adenocarcinoma in CRC patients(P<0.05).Drawing receiver operating characteristic(ROC)curves showed that,the areas under the curve of arterial phase IC,arterial phase NIC,arterial phase Overlay value,arterial phase λHU,venous phase IC,venous phase Overlay value,and venous phase λHU in the identification of pathological types of CRC patients were 0.888,0.820,0.769,0.832,0.863,0.810,and 0.723,respectively.Conclusion:The arteriovenous phase IC,Overlay value,λHU and arterial phase NIC of different pathological type in CRC patients were significant difference,and the above CT energy spectrum parameters can provide objective reference for distinguishing pathological type.
维普
万方数据