首页|床旁超声膈肌功能评估对慢性阻塞性肺疾病机械通气撤机的预测价值

床旁超声膈肌功能评估对慢性阻塞性肺疾病机械通气撤机的预测价值

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目的:研究分析床旁超声膈肌功能评估对慢性阻塞性肺疾病(COPD)机械通气撤机的预测价值。方法:选取2022 年 4 月—2023 年 6 月凉山彝族自治州第一人民医院行机械通气的 60 例患者作为研究对象,在符合临床撤机条件后进行2 h自主呼吸试验(SBT)。试验结束后采用床旁超声对患者进行评估,按照撤机结果分为参照组(撤机失败,n=28)和试验组(撤机成功,n=32)。比较两组行SBT 30 min后吸气末膈肌厚度(DTei)、呼气末膈肌厚度(DTee)、膈肌增厚指数(DTF)、右侧膈肌移位距离(DD)、浅快呼吸指数(RSBI)及膈肌浅快呼吸指数(D-RSBI)等床旁超声膈肌功能评估相关参数,并应用受试者工作特征曲线(ROC)分析床旁超声功能评估相关参数在COPD机械通气患者撤机指导中应用效能。结果:两组行SBT 30 min后DTei、DTee比较,差异无统计学意义(P>0。05);试验组行SBT 30 min后DTF高于参照组,DD长于参照组,差异有统计学意义(P<0。05)。试验组行SBT 30 min后RSBI、D-RSBI低于参照组,差异有统计学意义(P<0。05)。曲线下面积(AUC)≥0。7 时,表示预测价值良好,DTF、DD、RSBI、D-RSBI均对撤机有较好的预测价值,其AUC依次为0。840、0。749、0。876、0。804;同时,DTF敏感度高于DD、RSBI、D-RSBI。结论:床旁超声膈肌功能评估获取DTF、RSBI及D-RSBI等参数在COPD撤机指导中应用效能良好,可为临床成功撤机提供良好预测价值。
Predictive Value of Bedside Ultrasound Diaphragm Function Assessment for Mechanical Ventilation Withdrawal in Chronic Obstructive Pulmonary Disease
Objective:To study and analyze the predictive value of bedside ultrasound diaphragm function assessment for mechanical ventilation withdrawal in chronic obstructive pulmonary disease(COPD).Method:A total of 60 patients who underwent mechanical ventilation in the First People's Hospital of Liangshan Yi Autonomous Prefecture from April 2022 to June 2023 were selected as the research objects,and 2 h spontaneous breathing test(SBT)was performed after meeting the clinical weaning conditions.After the end of the trial,the patients were evaluated by bedside ultrasound.According to the results of weaning,the patients were divided into the reference group(weaning failure,n=28)and the experimental group(weaning success,n=32).The relevant parameters of bedside ultrasound diaphragmatic function evaluation such as diaphragmatic thickness at the end of inspiration(DTei),diaphragmaticthickness at the end of expiration(DTee),diaphragmatic thickening fraction(DTF),diaphragmatic displacement(DD),rapid shallow breathing index(RSBI)and diaphragmatic rapid shallow breathing index(D-RSBI)were compared between two groups after 30 min of SBT.The receiver operating characteristic curve(ROC)was used to analyze the application efficiency of bedside ultrasound function evaluation related parameters in weaning guidance of COPD patients with mechanical ventilation.Result:There were no statistically significant differences in DTei and DTee between two groups after 30 min of SBT(P>0.05);the DTF of the experimental group after 30 min of SBT was higher than that of the reference group,and the DD was longer than that of the reference group,the differences were statistically significant(P<0.05).The RSBI and D-RSBI of the experimental group after 30 min of SBT were lower than those of the reference group,and the differences were statistically significant(P<0.05).When the area under the curve(AUC)≥0.7,it indicated that the predictive value was good.DTF,DD,RSBI and D-RSBI all had good predictive value for weaning,and their AUC were 0.840,0.749,0.876 and 0.804,respectively;at the same time,the sensitivity of DTF was higher than those of DD,RSBI and D-RSBI.Conclusion:The parameters of DTF,RSBI and D-RSBI obtained by bedside ultrasound diaphragmatic function assessment have good application efficacy in the guidance of COPD weaning,which can provide good predictive value for clinical successful weaning.

Bedside ultrasoundDiaphragm functionChronic obstructive pulmonary diseaseMechanical ventilation

刘真、刘国康

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凉山彝族自治州第一人民医院 四川 西昌 615000

床旁超声 膈肌功能 慢性阻塞性肺疾病 机械通气

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(11)
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