首页|胸腔镜微创手术与传统开胸手术治疗非小细胞肺癌患者的临床效果

胸腔镜微创手术与传统开胸手术治疗非小细胞肺癌患者的临床效果

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目的:分析非小细胞肺癌患者行胸腔镜微创手术与传统开胸手术治疗的临床价值。方法:回顾性分析 2017 年6 月—2023 年 6 月莒南县人民医院收治的 68 例非小细胞肺癌患者的临床资料,依据治疗方法不同将患者分为研究组(胸腔镜微创手术)和参照组(传统开胸手术),各 34 例。比较两组围手术期指标、心肺功能指标、炎症指标及并发症发生情况。结果:研究组手术用时、术后引流时间和住院天数短于参照组,术中出血量少于参照组,差异有统计学意义(P<0。05);两组淋巴结清扫数比较,差异无统计学意义(P>0。05)。两组术前心肺功能指标比较,差异无统计学意义(P>0。05);研究组术后心率、最大自主通气量(MVV)和第 1 秒用力呼气容积(FEV1)高于参照组,差异有统计学意义(P<0。05)。两组术前炎症指标比较,差异无统计学意义(P>0。05);研究组术后C反应蛋白(CRP)、白细胞介素-6(IL-6)水平低于参照组,白细胞介素-12(IL-12)水平高于参照组,差异有统计学意义(P<0。05)。两组术前视觉模拟评分法(VAS)评分比较,差异无统计学意义(P>0。05);研究组术后 12 h、24 h、72 h的VAS评分低于参照组,差异有统计学意义(P<0。05)。研究组术后并发症发生率低于参照组,差异有统计学意义(P<0。05)。结论:非小细胞肺癌患者胸腔镜微创手术治疗效果优于传统开胸手术,不仅改善心肺功能,同时降低并发症发生率,减轻疼痛,缩短手术用时和住院天数。
Clinical Effects of Thoracoscopic Minimally Invasive Surgery and Traditional Thoracotomy Surgery in the Treatment of Non-small Cell Lung Cancer Patients
Objective:To analyze the clinical value of thoracoscopic minimally invasive surgery and traditional thoracotomy surgery in the treatment of non-small cell lung cancer patients.Method:The clinical data of 68 patients with non-small cell lung cancer who admitted to Junan County People's Hospital from June 2017 to June 2023 were retrospectively analyzed,the patients were divided into study group(thoracoscopic minimally invasive surgery)and reference group(traditional thoracotomy surgery)according to different treatment methods,34 cases in each group.The perioperative indexes,cardiopulmonary function indexes,inflammatory indexes and complications were compared between the two groups.Result:The operation time,postoperative drainage time and hospitalization days of the study group were shorter than those of the reference group,and the intraoperative blood loss was less than that of the reference group,the differences were statistically significant(P<0.05);there was no significant difference in the number of lymph node dissection between two groups(P>0.05).There were no significant differences in the cardiopulmonary function indexes between two groups before surgery(P>0.05);the heart rate,maximal voluntary ventilation(MVV)and forced expiratory volume in one second(FEV1)in the study group after surgery were higher than those in the reference group,and the differences were statistically significant(P<0.05).There were no significant differences in the inflammatory indexes between two groups before surgery(P>0.05);the levels of C-reactive protein(CRP)and interleukin-6(IL-6)in the study group after surgery were lower than those in the reference group,and the level of interleukin-12(IL-12)was higher than that in the reference group,the differences were statistically significant(P<0.05).There was no significant difference in the visual analogue scale(VAS)score between two groups before surgery(P>0.05);the VAS scores of the study group at 12 h,24 h and 72 h after surgery were lower than those of the reference group,and the differences were statistically significant(P<0.05).The incidence of postoperative complications in the study group was lower than that in the reference group,and the difference was statistically significant(P<0.05).Conclusion:The effect of thoracoscopic minimally invasive surgery in patients with non-small cell lung cancer is better than that of traditional thoracotomy,it not only improves cardiopulmonary function,but also reduces the incidence of complications,relieves pain,and shortens the operation time and hospitalization days.

Thoracoscopic minimally invasive surgeryTraditional thoracotomy surgeryNon-small cell lung cancerComplicationsPerioperative indicators

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莒南县人民医院 山东 莒南 276600

胸腔镜微创手术 传统开胸手术 非小细胞肺癌 并发症 围手术期指标

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(12)
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