Application Effect of Remazolam Besylate in Painless Gastrointestinal Endoscopy in the Elderly
Objective:To investigate the analgesic effect of Remimazolam Besylate in elderly patients undergoing painless gastroenteroscopy.Method:A total of 70 elderly patients who underwent painless gastroenteroscopy in Chongqing Hongren First Hospital from January to December 2022 were selected to carry out this clinical practice study.They were divided into control group and observation group by random number table method,with 35 cases in each group.The anesthetic drug of the control group was Propofol,and the anesthetic drug of the observation group was Remimazolam Besylate.Hemodynamic indexes such as heart rate,mean arterial pressure and blood oxygen saturation before anesthesia induction(T0)and when gastroscopy was passed through the throat(T1)were compared between the two groups,as well as the sedation grade and the incidence of anesthetic-related adverse reactions during the examination.Result:At T0,there were no significant differences in hemodynamic indexes between the two groups(P>0.05).At T1,the heart rate,mean arterial pressure and blood oxygen saturation of the observation group compared with that of the T0,the differences were not statistically significant(P<0.05).The heart rate,mean arterial pressure and blood oxygen saturation of the control group at T1 were lower than those of T0,and the differences were statistically significant(P<0.05).The proportion of grade 1,grade 2 and grade 3 patients in observation group were lower than those in control group,and the proportion of grade 5 and grade 6 patients were higher than those in control group,the differences were statistically significant(P<0.05).The total incidence of anesthesia related adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Remimazolam Besylate during painless gastrointestinal endoscopy in elderly patients has a good effect on analgesia and can also stabilize the hemodynamics of patients and prevent the occurrence of anesthetic-related adverse reactions.
国家科技期刊平台
NSTL
万方数据
维普
