Effect of Tranexamic Acid on Patients Undergoing Monocondylar Replacement Surgery
Objective:To investigate the effect of Tranexamic Acid(TXA)on patients with monocondylar replacement surgery.Method:A total of 58 patients with monocondylar replacement surgery admitted to Huangshan Xinchen Hospital from June 2020 to December 2022 were selected.They were randomly divided into control group(n=28)and observation group(n=30).The observation group was given TXA and the control group was given sodium chloride injection.Perioperative indexes,blood loss volume,anemia indexes on 2 d,4 d and 6 d after surgery,and lower limb deep vein thrombosis(DVT)were compared between the two groups.Result:The area of subcutaneous ecchymosis around the knee joint in the observation group was smaller than that in the control group,and the difference was statistically significant(P<0.05).The intraoperative blood loss volume and recessive blood loss volume in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).On 2 d,4 d and 6 d after surgery,the levels of hemoglobin(Hb)and hematocrit(HCT)were increased in both groups,and the levels of Hb and HCT in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of lower limb DVT between the two groups(P>0.05).Conclusion:The use of TXA during monocondylar replacement surgery can reduce blood loss and improve anemia markers without increasing the risk of lower limb DVT.
国家科技期刊平台
NSTL
万方数据
维普
