Effect of Electronic Bronchoscope Alveolar Lavage on Clinical Pulmonary Infection Score,Pulmonary Function and Inflammatory Indexes in Elderly Patients with Severe Pneumonia Complicated with Respiratory Failure
Objective:To explore the effect of electronic bronchoscope alveolar lavage on clinical pulmonary infection score(CPIS),pulmonary function and inflammatory indexes in elderly patients with severe pneumonia complicated with respiratory failure.Method:Eighty-five elderly patients with severe pneumonia complicated with respiratory failure who admitted to the Respiratory Department of Lijin Central Hospital from June 2021 to June 2023 were selected as the study objects,the patients were divided into the control group(42 cases)and the experimental group(43 cases)according to random number table method.The control group was given comprehensive treatment measures such as conventional antiviral,anti-infection and ventilator,while the experimental group was given electronic bronchoscope alveolar lavage on the basis of the control group,the clinical efficacy,serum inflammatory indexes,pulmonary function indexes,respiratory mechanics indexes and CPIS score were compared between two groups.Result:The effective rate of the experimental group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in the serum inflammatory indexes between two groups(P>0.05);after treatment,the white blood cell count(WBC),C-reactive protein(CRP),peripheral blood neutrophil to lymphocyte ratio(NLR)and procalcitonin(PCT)in two groups were lower than those before treatment,and which in the experimental group were lower than the control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in the pulmonary function indexes between two groups(P>0.05);after treatment,the forced expiratory volume in one second(FEV1),maximum ventilation volume(MMV),maximum mid-expiratory flow(MMEF),total lung capacity(TLC)and functional residual capacity(FRC)in two groups were higher than those before treatment,and those in the experimental group were higher than those in the control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in the respiratory mechanics indexes between two groups(P>0.05);after treatment,the airway resistance(RAW)and work of breathing(WOB)in two groups were lower than those before treatment,and the pulmonary dynamic compliance(Cdyn)were higher than those before treatment,and the RAW and WOB in the experimental group were lower than those in the control group,and Cdyn was higher than that in the control group,the differences were statistically significant(P<0.05).Before treatment,there was no significant difference in CPIS score between two groups(P>0.05);after treatment,the CPIS scores of two groups were lower than those before treatment,and that in the experimental group was lower than that in the control group,the differences were statistically significant(P<0.05).Conclusion:The use of electronic bronchoscope alveolar lavage in elderly patients with severe pneumonia complicated with respiratory failure can achieve good results,improve pulmonary function indexes,respiratory mechanics indexes and CPIS scores,and reduce serum inflammatory indexes,thereby improving clinical efficacy.
Severe pneumoniaElectronic bronchoscopeAlveolar lavageRespiratory failurePulmonary functionInflammatory indexesClinical pulmonary infection score
国家科技期刊平台
NSTL
万方数据
维普
