Clinical Effect of Tuihuang Granules Draft by Oneself in the Treatment of Hyperbilirubinemia in Newborns with Dampness-heat Depression and Steaming Type
Objective:To investigate the clinical effect of Tuihuang Granules draft by oneself in the treatment of hyperbilirubinemia in newborns with dampness-heat depression and steaming type.Method:Eighty newborns with damp-heat depression and steaming type hyperbilirubinemia treated in Traditional Chinese Medicine Hospital of Ningde from January 2020 to August 2023 were selected as the study objects.According to the method of random number table,they were divided into control group and experimental group,40 cases in each group.The control group was given conventional treatment,and the experimental group was given self-designed Tuihuang Granules.The clinical efficacy,traditional Chinese medicine syndrome score before and after treatment,percutaneous bilirubin value before treatment,after 3 d of treatment and after 5 d of treatment,jaundice resolution time and adverse reactions were compared between the two groups.Result:The total effective rate of experimental group was higher than that of control group,and the difference was statistically significant(P<0.05).After treatment,skin yellowing,sclera yellowing,urine color,stool frequency,milk volume and irritability score of both groups were decreased,and skin yellowing,sclera yellowing,urine color,stool frequency,milk volume and irritability score of experimental group were lower than those of control group,the differences were statistically significant(P<0.05).After 3 d and 5 d of treatment,the percutaneous bilirubin value of both groups decreased,and the percutaneous bilirubin value of experimental group was lower than that of control group,the differences were statistically significant(P<0.05).The elimination time of jaundice in experimental group was shorter than that in control group,the difference was statistically significant(t=6.438,P<0.001).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Applying self-made Tuihuang Granules to treat neonatal hyperbilirubinemia can significantly improve the therapeutic effect,reduce traditional Chinese medicine syndrome scores and transcutaneous bilirubin level,and shorten the time for jaundice regression,without increasing the incidence of adverse reactions.
Neonatal hyperbilirubinemiaDamp-heat depression and steaming typeTuihuang GranulesTherapeutic effect
万方数据
维普
