Objective:To evaluate the effect of intercostal nerve block+intravaginal Morphine injection on patients undergoing video-assisted thoracoscopic surgery(VATS).Method:A total of 90 VATS patients admitted to Affiliated Hospital of Yangzhou University from March to November 2022 were selected.According to random number method,the patients were divided into intercostal nerve block group(L group),intercostal nerve block+intravaginal Morphine injection group(LQ group)and control group(C group),with 30 cases in each group.LQ group was given intercostal nerve block+intrathecal Morphine injection,L group was given intercostal nerve block,C group was not treated.Perioperative indexes,related indexes,pain degree at 30 min after wakefulness(T0),4 h after surgery(T1),8 h after surgery(T2),12 h after surgery(T3),18 h after surgery(T4),24 h after surgery(T5),48 h after surgery(T6)and adverse reactions were compared among the three groups.Result:There was no significant difference in operation time and single lung ventilation time among the three groups(P>0.05).From T1～6,the resting and exercise numerical rating scale(NRS)scores of LQ group were significantly lower than those of C group,the resting and exercise NRS scores of the LQ group were lower than those of the L group from T2～6,and the differences were statistically significant(P<0.05).The effective pressing times of patient controlled intravenous analgesia(PCIA)and the rate of remedial analgesia in LQ group were significantly lower than those in L group and C group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions among the three groups(P>0.05).Conclusion:Intravaginal Morphine analgesia can provide good bridging analgesia for single intercostal nerve block in patients with thoracoscopic below lobectomy,reduce the use of opioids,and facilitate patient recovery.
维普
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