Application Effect of Epidural Anesthesia Combined with General Anesthesia in Surgery for Degenerative Lumbar Spinal Stenosis in Elderly
Objective:To explore the application effect of epidural anesthesia combined with general anesthesia in surgery for degenerative lumbar spinal stenosis in elderly.Method:A total of 92 elderly patients with degenerative lumbar spinal stenosis who admitted to the Nuclear Industry 417 Hospital from August 2022 to August 2023 were selected as the research objects,the patients were divided into the control group and the study group according to the random number table method,with 46 cases in each group.The control group was treated with general anesthesia,and the study group was combined with epidural anesthesia on the basis of the control group.The anesthetic effect and perioperative related indicators of two groups were compared.Result:The visual analogue scale(VAS)score at 2 h(T2)and 6 h(T3)after operation and incidence of adverse reactions in the study group were lower than those in the control group,the onset time of anesthesia was shorter than that in the control group,the duration of continuous analgesia was longer than that in the control group,and the dosage of analgesic drugs within 24 h after operation was less than that in the control group,the differences were statistically significant(P<0.05).The mean arterial pressure,heart rate and malondialdehyde(MDA)level at T3 in the study group were lower than those in the control group,the superoxide dismutase(SOD)level was higher than that in the control group,the Kolcaba comfort score at 12 h after operation(T4)and the recovery quality score at T2 were higher than those in the control group,and the recovery time was shorter than that in the control group,the differences were statistically significant(P<0.05).Conclusion:The application effect of epidural anesthesia combined with general anesthesia in surgery for degenerative lumbar spinal stenosis in elderly is good,which can promote the stability of hemodynamic indicators such as heart rate and mean arterial pressure,reduce postoperative pain,improve awakening quality,alleviate oxidative stress stimulation,accelerate prognosis and recovery,and reduce the risk of adverse reactions,it has higher practicality and safety.
Epidural anesthesiaGeneral anesthesiaSurgery for degenerative lumbar spinal stenosis in elderlyOxidative stress stimulationHemodynamicsAnesthesia quality
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