首页|大脑前动脉血流动力学指标在新生儿缺氧缺血性脑病中的诊断价值

大脑前动脉血流动力学指标在新生儿缺氧缺血性脑病中的诊断价值

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目的:探究大脑前动脉血流动力学指标在新生儿缺氧缺血性脑病(HIE)中的诊断价值.方法:选取 2022 年2 月—2023 年 6 月莆田市第一医院收治的 80 例HIE患儿纳入HIE组,并选取同期收治的 80 例健康新生儿纳入非HIE组.两组均行颅脑超声检查.比较两组大脑前动脉收缩期峰值流速(PSV)、舒张末期流速(EDV)、阻力指数(RI)水平.分析大脑前动脉的PSV、EDV、RI对HIE的诊断价值.结果:HIE组PSV、EDV均低于非HIE组,RI高于非HIE组,差异有统计学意义(P<0.05).大脑前动脉PSV、EDV、RI单一诊断及联合诊断HIE的AUC为 0.875、0.878、0.877、0.915,当PSV、EDV、RI的截断值取 32.225 cm/s、11.355 cm/s、0.735 时,可获得最佳诊断效能,且联合诊断的价值较高.结论:HIE患儿的大脑前动脉PSV、EDV水平较低,RI水平较高,颅脑超声检测大脑前动脉PSV、EDV、RI可为HIE的诊断提供可靠依据.
The Diagnostic Value of Hemodynamic Indicators of the Anterior Cerebral Artery in Neonatal Hypoxic-ischemic Encephalopathy
Objective:To explore the diagnostic value of hemodynamic indicators of the anterior cerebral artery in neonatal hypoxic-ischemic encephalopathy(HIE).Method:Eighty children with HIE treated in the Putian First Hospital from February 2022 to June 2023 were included in the HIE group,and 80 healthy newborns treated in the same period were included in the non-HIE group.Brain ultrasonography examination was performed in both groups.The peak systolic flow velocity(PSV),end-diastolic flow velocity(EDV)and resistance index(RI)of anterior cerebral artery were compared between the two groups.The diagnostic value of PSV,EDV and RI in anterior cerebral artery for HIE was analyzed.Result:PSV and EDV in HIE group were lower than those in non-HIE group,and RI was higher than that in non-HIE group,the differences were statistically significant(P<0.05).The AUC of PSV,EDV and RI for single diagnosis and combined diagnosis of HIE were 0.875,0.878,0.877 and 0.915,and the best diagnostic efficiency could be obtained when the cut-off values of PSV,EDV and RI were 32.225 cm/s,11.355 cm/s and 0.735.And the value of combined diagnosis is higher.Conclusion:The level of PSV and EDV in the anterior cerebral artery of HIE children is low,and the level of RI is high.Craniocerebral ultrasound detection of PSV,EDV and RI in the anterior cerebral artery can provide reliable basis for the diagnosis of HIE.

Neonatal hypoxic-ischemic encephalopathyBrain ultrasoundAnterior cerebral arteryHemodynamicsDiagnosis

林美燕、蔡丽霞

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莆田市第一医院 福建 莆田 351100

新生儿缺氧缺血性脑病 颅脑超声 大脑前动脉 血流动力学 诊断

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(13)
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