Clinical Efficacy of Octreotide Combined with Gastroscopy in the Treatment of Peptic Ulcer Patients with Bleeding
Objective:To analyze the clinical effect of Octreotide combined with gastroscopy in the treatment of peptic ulcer with bleeding.Method:A total of 200 patients with peptic ulcer with bleeding admitted to the Qujing No.1 Hospital from January 2021 to January 2023 were selected as the study objects,and they were divided into control group and observation group according to different treatment methods,with 100 cases in each group.The control group was treated with gastroscopy,and the observation group was treated with Octreotide on the basis of the control group.Symptom remission time,hospital stay,pain degree,inflammatory factor index and quality of life were compared between the two groups.Result:After treatment,the time of abdominal pain relief,hematemesis stop time and hospital stay in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).At 24 h and 48 h after treatment,visual analogue scale(VAS)scores in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,interleukin-2(IL-2)in observation group was higher than that in control group,interleukin-6(IL-6)was lower than that in control group,the differences were statistically significant(P<0.05).After treatment,the MOS item short from health survey(SF-36)scores in each dimension of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion:Octreotide combined with gastroscopy in the treatment of peptic ulcer patients with bleeding can quickly relieve the hematemesis and pain symptoms of patients,regulate the indicators of inflammatory factors,improve the quality of life of patients,and promote the early recovery and discharge of patients.
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